Lions vs. Steelers Week 16 Dunkel NFL Picks, Predictions and Odds

The Detroit Lions (8-6) are considered favorites (-6.5) according to the oddsmakers ahead of their game versus the Pittsburgh Steelers (8-6) on December 21, 2025, starting at 4:25 p.m. ET, airing on CBS. The over/under for this one is set at 52.5 points.

The Lions sport the 21st-ranked defense this year (337.9 yards allowed per game), and they've been more effective offensively, ranking fourth-best with 379.9 yards per game. From an offensive perspective, the Steelers are compiling 24.0 points per game (13th-ranked). They rank 18th in the NFL on the other side of the ball (23.3 points allowed per game).

Lions vs. Steelers Odds and Game Time

• Date: Sunday, December 21, 2025
• Time: 4:25 p.m. ET
• City: Detroit, Michigan
• Venue: Ford Field
• Total: 52.5 points
• Spread: Lions -6.5
• Moneyline: Lions (-345), Steelers (+275)

How to watch Lions vs. Steelers

• TV Channel: CBS (KBAK-Bakersfield, CA)
• Live Stream: Fubo

Betting the Over/Under: Lions vs. Steelers

• The Lions and their opponents have scored more than 52.5 combined points eight times this season.
• In Detroit's 14 games this season, the combined scoring has gone over the point total nine times.
• The Steelers have combined with their opponent to score more than 52.5 points in four of 14 games this season.
• In Pittsburgh's 14 contests this season, the combined scoring has gone over the point total eight times.
• The teams combine to score 54.6 points per game, 2.1 more points than this matchup's total.
• These teams give up 47.9 points per game combined, 4.6 points fewer than this matchup's total.

Betting the Spread: Lions vs. Steelers

• Detroit has won seven games against the spread this season, while failing to cover seven times.
• Detroit is 3-2 ATS this season when playing as at least 6.5-point favorites.
• The Steelers have compiled a 7-7-0 record against the spread this year.
• The Lions are 4-3 against the spread, and 5-2 overall, at home.
• At home, as 6.5-point favorites or more, Detroit has one win ATS (1-2).
• Away from home, the Steelers have two wins against the spread and are 3-3 overall.

Betting the Moneyline: Lions vs. Steelers

• Detroit has been favored on the moneyline nine total times this season. They've gone 7-2 in those games.
• The Steelers have won three of the seven games they've played as underdogs this season.
• Detroit has a record of 4-1 when playing as a moneyline favorite with odds of -345 or shorter (80%).
• Pittsburgh has not entered a game this season as a bigger underdog on the moneyline than the +275 odds on them winning this game.
• The implied moneyline probability for this matchup gives the Lions a 77.5% chance to win.

Dunkel Prediction for Lions vs. Steelers

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