Guardians vs. Twins Dunkel MLB Picks, Predictions and Prop Bets - May 8

The Cleveland Guardians and Minnesota Twins square off in the first of a three-game series on Friday at Progressive Field, at 7:15 p.m. ET. Parker Messick (3-1, 2.40 ERA) gets the start for the Guardians, who are 20-19 this season and first in the AL Central. Connor Prielipp (1-0, 3.86 ERA) is expected to start for the Twins, who are 16-22 and fifth in the AL Central.

The Twins (+121) are on the road versus the favored Guardians (-143). The contest has an over/under set at 7.5.

Guardians vs. Twins Odds, Game Time

• Game day: Friday, May 8, 2026
• Game time: 7:15 p.m. ET
• Location: Cleveland, Ohio
• Stadium: Progressive Field
• Favorite: Guardians (-143)
• Underdog: Twins (+121)
• Over/under: 7.5

How to Watch Guardians vs. Twins

• TV Channel: Apple TV+
• Live Stream: Fubo (Watch for free)

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Guardians vs. Twins: Betting the Moneyline

• The Guardians have gone 9-9 in games they were favored on the moneyline (winning 50% of those games).
• Minnesota has been underdogs in 27 games this season and has come away with the win 12 times (44.4%) in those contests.
• Cleveland has played as favorites of -143 or more twice this season and split those games.
• The Twins have a win-loss record of 6-5 when favored by +121 or worse by sportsbooks this year.
• Based on this contest's moneyline, the Guardians have an implied win probability of 58.8%.
• The moneyline set for this matchup implies the Twins have a 45.2% chance of walking away with the win.

Guardians vs. Twins: Betting the Spread & Total

• The Guardians have played in 39 games with over/under set, and have combined with opponents to go over the total 19 times (19-20-0).
• So far this season, Minnesota and its opponents have hit the over in 22 of its 38 games with a total.
• The Guardians have covered 53.8% of their games this season, going 21-18-0 ATS.
• The Twins have an against the spread mark of 18-20-0 in 38 games with a line this season.