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Guardians vs. Athletics Dunkel MLB Picks, Predictions and Prop Bets - Sept. 20

20 September 2026 By Data Skrive

Angel Martinez leads the Cleveland Guardians into a matchup against the Athletics after his two-homer outing in a 12-6 victory over the Athletics. It starts at 1:40 p.m. ET on Sunday. Gavin Williams (13-8, 3.78 ERA) will start for the Guardians, who are 80-75 this season and first in the AL Central. Jack Perkins (3-11, 6.14 ERA) is expected to start for the Athletics, who are 61-94 and fourth in the AL West.

Bookmakers have made the Guardians a decent moneyline favorite (-248) at home over the Athletics (+196). The game's over/under is set at 7.

Guardians vs. Athletics Odds, Game Time

  • Game day: Sunday, September 20, 2026
  • Game time: 1:40 p.m. ET
  • Location: Cleveland, Ohio
  • Stadium: Progressive Field
  • Favorite: Guardians (-248)
  • Underdog: Athletics (+196)
  • Over/under: 7

How to Watch Guardians vs. Athletics

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Guardians vs. Athletics: Betting the Moneyline

  • The Guardians have won 53.6% of the games this season when they were the moneyline favorite (52-45).
  • The Athletics have been chosen as underdogs in 119 games this year and have walked away with the win 45 times (37.8%) in those games.
  • The Guardians have not entered a game this season with shorter moneyline odds than -248.
  • This year, the Athletics have won three of seven games when listed as at least +196 or better on the moneyline.
  • The Guardians have an implied moneyline win probability of 71.3% in this matchup.
  • The moneyline set for this matchup implies the Athletics have a 33.8% chance of walking away with the win.

Guardians vs. Athletics: Betting the Spread & Total

  • The Guardians have played in 155 games with a set over/under, and have combined with their opponents to go over the total 75 times (75-78-2).
  • Games involving the Athletics have gone over the total set by sportsbooks in 79 of 155 chances this season.
  • The Guardians have covered 47.7% of their games this season, going 74-81-0 ATS.
  • The Athletics have posted a record of 73-82-0 against the spread this season.
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