Cavaliers vs. Pacers Dunkel NBA Picks, Predictions and Odds - Nov. 21

The Indiana Pacers (2-13) will aim to end an eight-game road slide when squaring off against the Cleveland Cavaliers (10-6) on November 21, 2025 at Rocket Arena.

The Cavaliers square off against the Pacers in a game that Cleveland is currently a double-digit favorite by 13.5 points. The matchup's over/under is 239.5.

Cavaliers vs. Pacers Odds and Game Time

• Game day: Friday, November 21, 2025
• Game time: 7 p.m. ET
• Location: Cleveland, Ohio
• Arena: Rocket Arena
• Total: 239.5 points
• Spread: Cavaliers -13.5
• Moneyline: Cavaliers (-901), Pacers (+610)

How to watch Cavaliers vs. Pacers

• TV Channel: Amazon Prime Video

Betting the Over/Under: Cavaliers vs. Pacers

• Cavaliers games this season have gone over this contest's total of 239.5 points six times.
• The Pacers and their opponents have combined to score more than 239.5 points in four of 15 games this season.
• The teams average 230 points per game combined, 9.5 fewer than this matchup's total.
• Combined, these teams allow 239.2 points per game, 0.3 fewer points than this matchup's total.

Betting the Spread: Cavaliers vs. Pacers

• Cleveland has covered six times in 16 matchups with a spread this season.
• The Cavaliers have been favored by 13.5 points or more once this season, and covered the spread.
• The Pacers have won six games against the spread this year, while failing to cover nine times.
• The Cavaliers are 6-3 overall, and 3-6 against the spread, at home.
• The Pacers have two wins against the spread, and are 0-8 overall, on the road.

Betting the Moneyline: Cavaliers vs. Pacers

• The Cavaliers have put together a 9-5 record in games they were listed as the moneyline favorite (winning 64.3% of those games).
• The Pacers have won two, or 15.4%, of the 13 games they've played as underdogs this season.
• Cleveland has not yet played as a moneyline favorite of -901 or shorter.
• Indiana has not entered a game this season with longer moneyline odds than +610.
• Based on this contest's moneyline, the Cavaliers' implied win probability is 90.0%.

Dunkel Index Prediction for Cavaliers vs. Pacers

• Pick ATS: Cavaliers (- 13.5)
• Pick OU: Over (239.5)
  
• Prediction: Cavaliers 130 - Pacers 114
• Check out the rest of our Dunkel Index NBA Picks!