Clemson vs. South Carolina Dunkel Predictions & Vegas Odds - Dec. 16

The Clemson Tigers (8-3) take on the South Carolina Gamecocks (7-3) as 12.5-point favorites on Tuesday, December 16, 2025 at 7 p.m. ET on ESPN2. The point total is 139.5 in the matchup.

In its most recent matchup on Saturday, Clemson claimed a 70-63 victory against Mercer. In Clemson's win, Dillon Hunter led the way with a team-high 15 points (adding two rebounds and two assists). South Carolina is coming off of a 71-55 victory over Citadel in its most recent game on Saturday. Meechie Johnson Jr. scored a team-leading 19 points for South Carolina in the victory.

Clemson vs. South Carolina Odds and Game Time

• When: Tuesday, December 16, 2025 at 7 p.m. ET
• Where: Littlejohn Coliseum in Clemson, South Carolina
• Spread favorite: Clemson -12.5
• Moneyline favorite: Clemson -901
• Moneyline underdog: South Carolina +595
• Over/Under: 139.5 points

How to watch Clemson vs. South Carolina

• TV Channel: ESPN2
• Live Stream: Fubo
• Check out the rest of our Dunkel Index NCAA Basketball Picks!

Betting the Over/Under: Clemson vs. South Carolina

• Clemson and its opponents have hit the over on this game's total (139.5 points) six times this season.
• This season, seven of South Carolina's games have finished with a combined score higher than 139.5 points.
• The over/under for the contest of 139.5 is 22.4 points fewer than the combined points per game averages for the Tigers (81.8 points per game) and the Gamecocks (80.1 points per game).
• These two teams surrender a combined 134.6 points per game, 4.9 points less than this contest's over/under.
• On average, Clemson has seen a 148.2-point over/under in its games this season, 8.7 more points than the over/under in this contest.
• South Carolina's games have an average over/under of 148.3 points this season, 8.8 more points than the over/under for this matchup.

Betting the Spread: Clemson vs. South Carolina

• Against the spread, Clemson is 6-5-0 this year.
• The Tigers are 3-3 ATS when favored by 12.5 points or more this season.
• South Carolina has four wins against the spread in 10 games this season.
• Clemson is 3-3 against the spread, and 6-0 overall, at home.
• This season, as a 12.5-point favorite or greater at home, Clemson is 3-3 ATS.

Betting the Moneyline: Clemson vs. South Carolina

• This season, Clemson has won eight out of the nine games in which it has been the moneyline favorite.
• The Tigers have entered six games this season favored by -901 or more, and won each of those games.
• Clemson has a 90% chance to win this game based on the implied probability of the moneyline.
• South Carolina was defeated in both of the match ups it has played as moneyline underdogs this season.
• The Gamecocks have yet to play a game this season with longer moneyline odds than +595.
• South Carolina has an implied victory probability of 14.4% according to the moneyline set by sportsbooks for this matchup.