Reds vs. Astros Dunkel MLB Picks, Predictions and Prop Bets - May 8

The Cincinnati Reds and Houston Astros clash on Friday at 6:10 p.m. ET, opening a three-game series at Great American Ball Park. Nick Lodolo (0-0, 0.00 ERA) gets the start for the Reds, who are 20-18 this season and fifth in the NL Central. Mike Burrows (1-4, 5.97 ERA) is the expected starter for the Astros, who are 15-23 and fifth in the AL West.

The oddsmakers have spoken, making the Reds (-141) a moderate moneyline favorite to beat the Astros (+119) at home. The over/under for the Reds-Astros game is set at 9.

Reds vs. Astros Odds, Game Time

• Game day: Friday, May 8, 2026
• Game time: 6:10 p.m. ET
• Location: Cincinnati, Ohio
• Stadium: Great American Ball Park
• Favorite: Reds (-141)
• Underdog: Astros (+119)
• Over/under: 9

How to Watch Reds vs. Astros

• TV Channel: CINR and SCHN
• Live Stream: Fubo (Watch for free)

Bet now on FanDuel Sportsbook!

Reds vs. Astros: Betting the Moneyline

• The Reds have won 60% of the games this season when they were the moneyline favorite (6-4).
• Houston has won in 10, or 45.5%, of the 22 contests it has been named as odds-on underdogs in this year.
• Cincinnati has entered four games this season favored by -141 or more and is 2-2 in those contests.
• The Astros have a mark of 4-8 in contests where sportsbooks favor them by +119 or worse on the moneyline.
• The Reds have a 58.5% chance to win this contest based on the moneyline's implied probability.
• The Astros have an implied victory probability of 45.7% according to the moneyline set for this matchup.

Reds vs. Astros: Betting the Spread & Total

• The Reds have played in 38 games with set over/under, and have combined with opponents to go over the total 23 times (23-14-1).
• Houston's games have gone over the total in 25 of its 38 chances.
• The Reds have covered 63.2% of their games this season, going 24-14-0 ATS.
• The Astros are 15-23-0 against the spread in their 38 games that had a posted line this season.