White Sox vs. Royals Dunkel MLB Picks, Predictions and Prop Bets - Sept. 23

The Kansas City Royals will aim to snap a five-game losing streak when hosting the Chicago White Sox at 7:40 p.m. ET on Wednesday. Bryan Hudson (5-4, 3.03 ERA) gets the start for the White Sox, who are 81-76 this season and second in the AL Central. Seth Lugo (7-9, 5.06 ERA) is expected to start for the Royals, who are 67-90 and fifth in the AL Central.

The moneyline odds for the game between the White Sox (-118) and Royals (-103) suggest a close contest. The total for the White Sox-Royals game is set at 8.5.

White Sox vs. Royals Odds, Game Time

• Game day: Wednesday, September 23, 2026
• Game time: 7:40 p.m. ET
• Location: Kansas City, Missouri
• Stadium: Kauffman Stadium
• Favorite: White Sox (-118)
• Underdog: Royals (-103)
• Over/under: 8.5

How to Watch White Sox vs. Royals

• TV Channel: ROYL and CHSN
• Live Stream: Fubo (Watch for free)

Bet now on FanDuel Sportsbook!

White Sox vs. Royals: Betting the Moneyline

• The White Sox have won 56.2% of the games this season when they were favored on the moneyline (27-21).
• Kansas City has won in 40, or 38.8%, of the 103 contests it has been named as odds-on underdogs in this year.
• Chicago has a record of 18-13 in games when sportsbooks favor them by at least -118 on the moneyline.
• This season, the Royals have come away with a win 34 times in 89 chances when named as an underdog of at least -103 or worse on the moneyline.
• The White Sox have a 54.1% chance to win this game based on the moneyline's implied probability.
• The Royals have an implied victory probability of 50.7% according to the moneyline set for this matchup.

White Sox vs. Royals: Betting the Spread & Total

• The White Sox have played in 157 games with set over/under, and have combined with opponents to go over the total 90 times (90-66-1).
• Kansas City and its opponents have gone over the total this season in 69 of its 157 opportunities.
• The White Sox have a 90-67-0 record against the spread this season (covering 57.3% of the time).
• The Royals have posted a record of 75-82-0 against the spread this season.