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Cubs vs. Reds Dunkel MLB Picks, Predictions and Prop Bets - May 4

04 May 2026 By Data Skrive

The Cincinnati Reds hope to stop their three-game losing run versus the Chicago Cubs, at 7:40 p.m. ET on Monday. Edward Cabrera (3-0, 3.06 ERA) will start for the Cubs, who are 22-12 this season and first in the NL Central. Chase Petty (0-0, 0.00 ERA) is the expected starter for the Reds, who are 20-14 and second in the NL Central.

The Cubs are moderate favorites on the moneyline (-208) at home over the Reds (+172). The over/under for the Cubs-Reds game is set at 11.5.

Cubs vs. Reds Odds, Game Time

  • Game day: Monday, May 4, 2026
  • Game time: 7:40 p.m. ET
  • Location: Chicago, Illinois
  • Stadium: Wrigley Field
  • Favorite: Cubs (-208)
  • Underdog: Reds (+172)
  • Over/under: 11.5

How to Watch Cubs vs. Reds

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Cubs vs. Reds: Betting the Moneyline

  • The Cubs have gone 15-7 in games they were listed as the moneyline favorite (winning 68.2% of those games).
  • Cincinnati has been pegged as an underdog in 24 games this year and has walked away with the win 14 times (58.3%) in those games.
  • Chicago has a record of 1-2 in games when sportsbooks favor them by at least -208 on the moneyline.
  • Oddsmakers have given the Reds the worst odds of winning they have seen this season with a +172 moneyline listed for this contest.
  • The Cubs have an implied moneyline win probability of 67.5% in this contest.
  • The moneyline set for this matchup implies the Reds have a 36.8% chance of coming away with a victory in the contest.

Cubs vs. Reds: Betting the Spread & Total

  • In the 34 games in which bookmakers have set an over/under for the Cubs, they have combined with opponents to go over the total 22 times (22-10-2).
  • Cincinnati and its opponents have gone over the total this season in 21 of its 34 opportunities.
  • The Cubs are 17-17-0 ATS this season.
  • The Reds are 21-13-0 against the spread in their 34 games that had a posted line this season.
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