NBA Same Game Parlay: Cavaliers vs. Pacers – Friday, Nov. 21

The Indiana Pacers (2-13) will visit the Cleveland Cavaliers (10-6) after losing eight road games in a row. The contest starts at 7 p.m. ET on Friday, November 21, 2025. Below, we offer same-game parlay picks for you to consider for this contest.

Friday's game, which features the Cavaliers playing the Pacers, has the Cavaliers as a double-digit favorite by 14.5 points. The matchup has been given a point total of 239.5.

Cavaliers vs. Pacers: Odds and Game Info

• When: Friday, November 21, 2025 at 7 p.m. ET
• Where: Rocket Arena in Cleveland, Ohio
• TV: Amazon Prime Video

Cavaliers vs. Pacers: Potential Same Game Parlay

Here's a possible Cavaliers-Pacers same-game parlay you could place by betting on the spread, total and Donovan Mitchell over 28.5 points. Combining these three bets into a same-game parlay pays out $59.58 on a $10 bet.

• Spread Pick: Cavaliers (-14.5)
• Total Pick: Over (239.5)

Cavaliers vs. Pacers: Betting Insights

• In six games this season, the Cavaliers and their opponents have scored more than 239.5 combined points.
• Indiana has combined with its opponent to score more than 239.5 points in four of 15 games this season.
• The teams combine to score 230 points per game, 9.5 fewer points than this matchup's total.
• The Cavaliers' record against the spread is 6-10-0.
• The Pacers' ATS record is 6-9-0 this season.

Pick with the best in the business! Get free picks for every game, every week at the Dunkel Index.

Donovan Mitchell Points Prop Insights

• Mitchell Points Prop: Over/Under 28.5
• Donovan Mitchell's 30.2 points per game average is 1.7 points more than Friday's over/under.
• Mitchell has gone up against a points prop bet in 14 games this season, and he's exceeded the total 10 times.

Cavaliers vs. Pacers: Stat Comparison