Panthers vs. Saints Week 15 Dunkel NFL Picks, Predictions and Odds

The Carolina Panthers (7-6) and New Orleans Saints (3-10) will meet in a matchup of two division rivals. The Panthers are small favorites (-2.5). The expected point total for the matchup is set at 40.5.

The Panthers rank fifth-worst in scoring offense (19 points per game), but they've played slightly better on defense, ranking 15th with 22.8 points allowed per game. The Saints rank third-worst in points per game (15.8), but they've been more effective on the defensive side of the ball, ranking 20th in the NFL with 24.2 points allowed per contest.

Panthers vs. Saints Odds and Game Time

• Date: Sunday, December 14, 2025
• Time: 4:25 p.m. ET
• City: New Orleans, Louisiana
• Venue: Caesars Superdome
• Total: 40.5 points
• Spread: Panthers -2.5
• Moneyline: Panthers (-155), Saints (+130)

How to watch Panthers vs. Saints

• TV Channel: FOX (WDBD-Jackson, MS)
• Live Stream: Fubo

Betting the Over/Under: Panthers vs. Saints

• The Panthers and their opponents have gone over 40.5 combined points in seven of 13 games this season.
• So far this season, seven of Carolina's 13 games have gone over the point total.
• The Saints have combined with their opponents to score more than 40.5 points in six of 13 games this season.
• In 2025, four New Orleans games have gone over the point total.
• These teams average a combined 34.8 points per game, 5.7 fewer points than this matchup's point total.
• These two teams surrender 47 points per game combined, 6.5 more points than the over/under for this contest.

Betting the Spread: Panthers vs. Saints

• Carolina has put together an 8-5-0 record against the spread this season.
• Carolina has been favored by 2.5 points or more this season once, and failed to cover the spread.
• The Saints have won five games against the spread this year, failing to cover eight times.
• New Orleans has an ATS record of 4-7 when playing as at least 2.5-point underdogs this year.
• The Saints have one win against the spread, and are 1-5 overall, at home this year.
• New Orleans is winless ATS (0-4) as 2.5-point underdogs or greater at home.
• The Panthers are 3-4 overall, and 4-3 against the spread, on the road.

Betting the Moneyline: Panthers vs. Saints

• Carolina has been the moneyline favorite only one other time so far this season, a game they lost.
• This season, the Saints have won two out of the 11 games, or 18.2%, in which they've been the underdog.
• Carolina has played as a moneyline favorite of -155 or shorter in only one game this season, which it lost.
• New Orleans has a record of 2-9 in games where oddsmakers have them as underdogs of at least +130 on the moneyline.
• The Panthers have an implied moneyline win probability of 60.8% in this contest.

Dunkel Prediction for Panthers vs. Saints

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