Butler vs. South Carolina Dunkel Predictions & Vegas Odds - Nov. 21

The Butler Bulldogs (3-1) host the South Carolina Gamecocks (4-0) at Colonial Hall, starting at 2 p.m. ET on Friday, November 21, 2025. The Gamecocks are 1.5-point underdogs in the game. The over/under in the matchup is set at 154.5.

Butler heads into this contest after an 87-85 loss to SMU on Saturday. In Butler's loss, Finley Bizjack led the way with a team-high 18 points (adding two rebounds and four assists). South Carolina is coming off of an 87-58 win over Radford in its last game on Tuesday. Elijah Strong scored 15 points in South Carolina's win, leading the team.

Butler vs. South Carolina Odds and Game Time

• When: Friday, November 21, 2025 at 2 p.m. ET
• Where: Colonial Hall in White Sulphur Springs, West Virginia
• Spread favorite: Butler -1.5
• Moneyline favorite: Butler -134
• Moneyline underdog: South Carolina +111
• Over/Under: 154.5 points

How to watch Butler vs. South Carolina

• TV Channel: CBS Sports Network
• Live Stream: Fubo
• Check out the rest of our Dunkel Index NCAA Basketball Picks!

Betting the Over/Under: Butler vs. South Carolina

• Butler and its opponent combined to score over 154.5 points, the current matchup's point total, in 13 of 35 games last year.
• Six of South Carolina's 32 games last season went over 154.5 total points scored.
• These two teams averaged a combined 144.5 points per game a season ago, 10.0 fewer points than the total of 154.5 set for this matchup.
• Opponents of the two teams averaged a combined 8.2 fewer points per game (146.3) last season than this matchup's over/under of 154.5 points.
• The average total Butler had set in matchups last year was 4.9 fewer points than this outing's point total.
• The average over/under in South Carolina's games in 2024 was 13.3 fewer points than the point total of 154.5 for this game.

Betting the Spread: Butler vs. South Carolina

• Butler put together a 17-18-0 record against the spread last season.
• When playing as at least 1.5-point favorites last season, the Bulldogs had an ATS record of 7-7.
• South Carolina covered 16 times in 32 games with a spread last year.
• When playing as at least 1.5-point underdogs last season, the Gamecocks had an ATS record of 10-11.
• At home last year, Butler was 9-8 overall and 6-11 against the spread.
• At home last season, as a 1.5-point favorite or greater, Butler was 4-7 ATS.
• Last season on the road, South Carolina was 3-8 against the spread and 1-10 overall.
• South Carolina was unbeaten ATS (1-0) as a 1.5-point underdog or more away from home.

Betting the Moneyline: Butler vs. South Carolina

• Butler went 11-3 in games it was favored on the moneyline last season (winning 78.6% of those games).
• The Bulldogs had a 10-2 record last year (winning 83.3% of their games) when playing as a moneyline favorite of -134 or shorter.
• Butler has a 57.3% chance to win this game based on the moneyline's implied probability.
• Last season, South Carolina won two out of the 20 games, or 10%, in which it was the underdog.
• The Gamecocks had a record of 1-18, a 5.3% win rate, when they were set as an underdog of +111 or more by oddsmakers last season.
• Oddsmakers have implied with the moneyline set for this matchup that South Carolina has a 47.4% chance to win.