Orioles vs. Blue Jays Dunkel MLB Picks, Predictions and Prop Bets - Sept. 21

The Baltimore Orioles and Toronto Blue Jays clash in the first of a three-game series on Monday at Oriole Park at Camden Yards, at 6:35 p.m. ET. Shane Baz (6-15, 4.11 ERA) gets the start for the Orioles, who are 75-81 this season and fifth in the AL East. Trey Yesavage (5-5, 3.65 ERA) is the expected starter for the Blue Jays, who are 77-79 and fourth in the AL East.

Bookmakers expect a close matchup between the Orioles (-112 to win) and the Blue Jays (-109). The contest has an over/under set at 7.5.

Orioles vs. Blue Jays Odds, Game Time

• Game day: Monday, September 21, 2026
• Game time: 6:35 p.m. ET
• Location: Baltimore, Maryland
• Stadium: Oriole Park at Camden Yards
• Favorite: Orioles (-112)
• Underdog: Blue Jays (-109)
• Over/under: 7.5

How to Watch Orioles vs. Blue Jays

• TV Channel: MASN and SNET
• Live Stream: Fubo (Watch for free)

Bet now on FanDuel Sportsbook!

Orioles vs. Blue Jays: Betting the Moneyline

• The Orioles have a 36-32 record in games they were favored on the moneyline (winning 52.9% of those games).
• Toronto has been pegged as an underdog in 71 games this year and has walked away with the win 32 times (45.1%) in those games.
• Baltimore has a record of 34-31 in games when sportsbooks favor them by at least -112 on the moneyline.
• This season, the Blue Jays have been victorious 30 times in 67 chances when named as an underdog of at least -109 or worse on the moneyline.
• The Orioles have a 52.8% chance to win this game based on the moneyline's implied probability.
• The moneyline set for this matchup implies the Blue Jays have a 52.2% chance of walking away with the win.

Orioles vs. Blue Jays: Betting the Spread & Total

• The Orioles have had an over/under set by oddsmakers 156 times, and have combined with opponents to go over the total in 79 of those games (79-74-3).
• Games involving Toronto have gone over the total set by sportsbooks in 80 of 156 chances this season.
• The Orioles have an 81-75-0 record against the spread this season (covering 51.9% of the time).
• The Blue Jays are 78-78-0 against the spread in their 156 games with a line set by sportsbooks this season.