Buccaneers vs. Panthers Week 16 Dunkel NFL Picks, Predictions and Odds

The Tampa Bay Buccaneers (7-7) are small favorites (-2.5) versus the Carolina Panthers (7-7) in a matchup of two division rivals. The expected point total for the matchup is set at 45.5.

The Buccaneers are compiling 316.6 yards per game on offense, which ranks them 22nd in the NFL. On defense, they rank 25th, surrendering 348.2 yards per game. The Panthers rank 24th with 309 total yards per game on offense, and they rank 17th with 331.5 total yards ceded per game on defense.

Buccaneers vs. Panthers Odds and Game Time

• Date: Sunday, December 21, 2025
• Time: 1 p.m. ET
• City: Charlotte, North Carolina
• Venue: Bank of America Stadium
• Total: 45.5 points
• Spread: Buccaneers -2.5
• Moneyline: Buccaneers (-155), Panthers (+130)

How to watch Buccaneers vs. Panthers

• TV Channel: FOX (WTWC-Tallahassee, FL - Thomasville, GA)
• Live Stream: Fubo

Betting the Over/Under: Buccaneers vs. Panthers

• The Buccaneers and their opponents have scored more than 45.5 total points seven times this season.
• A total of eight out of 14 Tampa Bay games this season have gone over the point total.
• Panthers games this season have had a combined scoring total higher than 45.5 points in seven of 14 outings.
• So far this year, seven of Carolina's 14 games with a set number have hit the over.
• The teams combine to score 42.3 points per game, 3.2 fewer points than this matchup's point total.
• Opponents of these teams put up 47.9 combined points per game, 2.4 more points than this contest's over/under.

Betting the Spread: Buccaneers vs. Panthers

• Tampa Bay has put together a 5-9-0 record against the spread this season.
• Tampa Bay has covered the spread twice when favored by 2.5 points or more this season (in seven opportunities).
• The Panthers have compiled an 8-6-0 record against the spread this season.
• Carolina is 6-4 ATS this season when playing as at least 2.5-point underdogs.
• At home this season, the Panthers are 4-2 against the spread and 4-2 overall.
• At home, as 2.5-point underdogs or more, Carolina is 3-1 ATS.
• This season in away games, the Buccaneers are 4-3 against the spread and 4-3 overall.
• Tampa Bay is unbeaten ATS (1-0) as 2.5-point favorites or more away from home.

Betting the Moneyline: Buccaneers vs. Panthers

• Tampa Bay has won five of the eight games it was favored on the moneyline this season (62.5%).
• The Panthers have been underdogs in 12 games this season and won seven (58.3%) of those contests.
• Tampa Bay is 4-2 (winning 66.7% of its games) when playing as a moneyline favorite of -155 or shorter.
• Carolina is 5-5 this season when entering a game as the underdog by +130 or more on the moneyline.
• Based on this contest's moneyline, the Buccaneers' implied win probability is 60.8%.

Dunkel Prediction for Buccaneers vs. Panthers

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