Cardinals vs. Nationals Dunkel MLB Picks, Predictions and Prop Bets - Sept. 20

The St. Louis Cardinals will aim to snap a four-game losing streak when hosting the Washington Nationals at 2:15 p.m. ET on Sunday. Quinn Mathews (2-3, 3.62 ERA) will start for the Cardinals, who are 75-80 this season and fourth in the NL Central. Jake Irvin (2-9, 5.51 ERA) is the expected starter for the Nationals, who are 73-82 and fourth in the NL East.

The Cardinals are moderate favorites on the moneyline (-132) at home over the Nationals (+108). The over/under in this contest is 8.5.

Cardinals vs. Nationals Odds, Game Time

• Game day: Sunday, September 20, 2026
• Game time: 2:15 p.m. ET
• Location: St. Louis, Missouri
• Stadium: Busch Stadium
• Favorite: Cardinals (-132)
• Underdog: Nationals (+108)
• Over/under: 8.5

How to Watch Cardinals vs. Nationals

• TV Channel: CARD and NATS
• Live Stream: Fubo (Watch for free)

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Cardinals vs. Nationals: Betting the Moneyline

• The Cardinals have been the moneyline favorite 52 total times this season. They've finished 26-26 in those games.
• Washington has won in 50, or 42.4%, of the 118 contests it has been named as odds-on underdogs in this year.
• St. Louis has a record of 9-7 in games when oddsmakers favor them by at least -132 on the moneyline.
• This season, the Nationals have come away with a win 37 times in 91 chances when named as an underdog of at least +108 or worse on the moneyline.
• Based on this matchup's moneyline, the Cardinals' implied win probability is 56.9%.
• The Nationals have an implied victory probability of 48.1% according to the moneyline set by oddsmakers for this matchup.

Cardinals vs. Nationals: Betting the Spread & Total

• The Cardinals have had an over/under set by bookmakers 155 times, and have combined with opponents to go over the total in 70 of those games (70-75-10).
• Games involving Washington have gone over the total set by sportsbooks in 82 of 155 chances this season.
• The Cardinals have an 84-71-0 record ATS this season (covering 54.2% of the time).
• The Nationals are 87-68-0 against the spread in their 155 games with a line set by sportsbooks this season.