Mariners vs. Angels Dunkel MLB Picks, Predictions and Prop Bets - Sept. 25

The Seattle Mariners host the Los Angeles Angels on Friday at T-Mobile Park, at 10:10 p.m. ET. Bryce Miller (4-9, 3.99 ERA) gets the start for the Mariners, who are 74-85 this season and third in the AL West. Reid Detmers (6-8, 3.47 ERA) is the expected starter for the Angels, who are 61-98 and fifth in the AL West.

The Mariners (-122) are moneyline favorites at home over the Angels (+100). The over/under in this contest is set at 6.5.

Mariners vs. Angels Odds, Game Time

• Game day: Friday, September 25, 2026
• Game time: 10:10 p.m. ET
• Location: Seattle, Washington
• Stadium: T-Mobile Park
• Favorite: Mariners (-122)
• Underdog: Angels (+100)
• Over/under: 6.5

How to Watch Mariners vs. Angels

• TV Channel: SEAM and ABTV
• Live Stream: Fubo (Watch for free)

Bet now on FanDuel Sportsbook!

Mariners vs. Angels: Betting the Moneyline

• The Mariners have put together a 61-62 record in games they were favored on the moneyline (winning 49.6% of those games).
• Los Angeles has been pegged as an underdog in 129 games this year and has walked away with the win 47 times (36.4%) in those games.
• Seattle has a record of 52-47, a 52.5% win rate, when favored by -122 or more by oddsmakers this season.
• This season, the Angels have come away with a win 40 times in 111 chances when named as an underdog of at least +100 or longer on the moneyline.
• Based on this matchup's moneyline, the Mariners have an implied win probability of 55%.
• Bookmakers have implied with the moneyline set for this matchup that the Angels have a 50% chance of pulling out a win.

Mariners vs. Angels: Betting the Spread & Total

• The Mariners have had an over/under set by oddsmakers 159 times, and have combined with opponents to go over the total in 82 of those games (82-68-9).
• So far this season, Los Angeles and its opponents have hit the over in 68 of its 159 games with a total.
• The Mariners are 58-101-0 against the spread this season.
• The Angels have posted a record of 81-78-0 against the spread this season.