Mariners vs. Angels Dunkel MLB Picks, Predictions and Prop Bets - Sept. 16

The Seattle Mariners carry a three-game losing run into a road contest versus the Los Angeles Angels, at 9:38 p.m. ET on Wednesday. George Kirby (9-11, 4.25 ERA) gets the start for the Mariners, who are 70-82 this season and third in the AL West. Yusei Kikuchi (1-5, 4.75 ERA) is the expected starter for the Angels, who are 58-93 and fifth in the AL West.

Despite playing away from their home ballpark, the Mariners are favored to win (-143) over the Angels (+117). The game's over/under is set at 7.5.

Mariners vs. Angels Odds, Game Time

• Game day: Wednesday, September 16, 2026
• Game time: 9:38 p.m. ET
• Location: Anaheim, California
• Stadium: Angel Stadium
• Favorite: Mariners (-143)
• Underdog: Angels (+117)
• Over/under: 7.5

How to Watch Mariners vs. Angels

• TV Channel: ABTV and SEAM
• Live Stream: Fubo (Watch for free)

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Mariners vs. Angels: Betting the Moneyline

• The Mariners have gone 57-59 in games they were favored on the moneyline (winning 49.1% of those games).
• Los Angeles has been underdogs in 125 games this season and has come away with the win 46 times (36.8%) in those contests.
• This season Seattle has won 30 of its 48 games, or 62.5%, when favored by at least -143 on the moneyline.
• This year, the Angels have won 29 of 81 games when listed as at least +117 or worse on the moneyline.
• Based on this contest's moneyline, the Mariners have an implied win probability of 58.8%.
• The moneyline set for this matchup implies the Angels have a 46.1% chance of walking away with the win.

Mariners vs. Angels: Betting the Spread & Total

• The Mariners have played in 152 games with an over/under set, and have combined with their opponents to go over the total 79 times (79-64-9).
• Games involving Los Angeles have gone over the total set by bookmakers in 62 of 151 chances this season.
• The Mariners have a 57-95-0 record ATS this season (covering only 37.5% of the time).
• The Angels have posted a record of 79-72-0 against the spread this season.