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Mariners vs. Guardians Dunkel MLB Picks, Predictions and Prop Bets - March 27

27 March 2026 By Data Skrive

Dominic Canzone leads the Seattle Mariners into a contest against the Cleveland Guardians after his two-homer performance in a 6-4 defeat to the Guardians. It begins at 9:45 p.m. ET on Friday. George Kirby (0-0, 0.00 ERA) gets the start for the Mariners, who are 0-1 this season and fourth in the AL West. Gavin Williams (0-0, 0.00 ERA) is the expected starter for the Guardians, who are 1-0 and first in the AL Central.

At home, the Mariners are favored to win on the moneyline (-174) over the Guardians (+146). The game has an over/under set at 7 runs.

Mariners vs. Guardians Odds, Game Time

  • Game day: Friday, March 27, 2026
  • Game time: 9:45 p.m. ET
  • Location: Seattle, Washington
  • Stadium: T-Mobile Park
  • Favorite: Mariners (-174)
  • Underdog: Guardians (+146)
  • Over/under: 7

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Mariners vs. Guardians: Betting the Moneyline

  • The Mariners put together a 67-51 record in games they were listed as the moneyline favorite last season (winning 56.8% of those games).
  • Cleveland was underdogs in 88 games last season and came away with the win 42 times (47.7%) in those contests.
  • Seattle had a record of 21-9 when it played as a moneyline favorite with odds of -174 or shorter last year (70%).
  • Last season, Cleveland came away with a win six times in 16 chances when named as an underdog of at least +146 or worse on the moneyline.
  • The implied moneyline probablility for this matchup gives the Mariners a 63.5% chance to win.
  • The moneyline set for this matchup implies the Guardians have a 40.7% chance of coming away with a victory in the contest.

Mariners vs. Guardians: Betting the Spread & Total

  • The Mariners combined with their opponents to hit the over on the total 95 times last season for a 95-74-5 record against the over/under.
  • Cleveland and its opponents hit the over in 67 of its 163 games with a total last season.
  • The Mariners collected a 77-97-0 record against the spread last season (covering 44.3% of the time).
  • In 163 games with a line last season, the Guardians had a mark of 86-77-0 against the spread.
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