Padres vs. Cardinals Dunkel MLB Picks, Predictions and Prop Bets - May 8

The San Diego Padres and St. Louis Cardinals meet on Friday at 9:45 p.m. ET. Griffin Canning (0-0, 1.80 ERA) will start for the Padres, who are 22-15 this season and second in the NL West. Michael McGreevy (2-2, 2.52 ERA) is expected to start for the Cardinals, who are 22-15 and second in the NL Central.

The bookmakers have spoken, making the Padres (-149) a moderate moneyline favorite to defeat the Cardinals (+124) at home. The total for the Padres-Cardinals game is set at 8.

Padres vs. Cardinals Odds, Game Time

• Game day: Friday, May 8, 2026
• Game time: 9:45 p.m. ET
• Location: San Diego, California
• Stadium: Petco Park
• Favorite: Padres (-149)
• Underdog: Cardinals (+124)
• Over/under: 8

How to Watch Padres vs. Cardinals

• TV Channel: Apple TV+
• Live Stream: Fubo (Watch for free)

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Padres vs. Cardinals: Betting the Moneyline

• The Padres have a 12-9 record in games they were listed as the moneyline favorite (winning 57.1% of those games).
• St. Louis has won in 20, or 60.6%, of the 33 contests it has been named as odds-on underdogs in this year.
• San Diego is 8-3 this season when entering a game favored by -149 or more on the moneyline.
• The Cardinals have a mark of 6-4 in contests where bookmakers favor them by +124 or worse on the moneyline.
• The implied moneyline probablility for this matchup gives the Padres a 59.8% chance to win.
• The Cardinals have an implied victory probability of 44.6% according to the moneyline set by oddsmakers for this matchup.

Padres vs. Cardinals: Betting the Spread & Total

• In the 37 games in which oddsmakers have set an over/under for the Padres, they have combined with opponents to go over the total 16 times (16-19-2).
• St. Louis' games have gone over the total in 17 of its 37 chances.
• The Padres have covered 56.8% of their games this season, going 21-16-0 ATS.
• The Cardinals are 23-14-0 against the spread in their 37 games with a line set by sportsbooks this season.