Padres vs. Giants Dunkel MLB Picks, Predictions and Prop Bets - May 5

The San Francisco Giants host the San Diego Padres at 9:45 p.m. ET on Tuesday. Walker Buehler (1-2, 5.40 ERA) gets the start for the Padres, who are 20-14 this season and second in the NL West. Logan Webb (2-3, 4.30 ERA) is expected to start for the Giants, who are 14-21 and fourth in the NL West.

Despite being on the road the Padres are a moderate moneyline favorite (-118) over the Giants (+100). The game has an over/under of 8.5 runs.

Padres vs. Giants Odds, Game Time

• Game day: Tuesday, May 5, 2026
• Game time: 9:45 p.m. ET
• Location: San Francisco, California
• Stadium: Oracle Park
• Favorite: Padres (-118)
• Underdog: Giants (+100)
• Over/under: 8.5

How to Watch Padres vs. Giants

• TV Channel: NBCS-BA and SDPA
• Live Stream: Fubo (Watch for free)

Bet now on FanDuel Sportsbook!

Padres vs. Giants: Betting the Moneyline

• The Padres have been favored on the moneyline 20 total times this season. They've gone 12-8 in those games.
• San Francisco has been victorious in nine, or 37.5%, of the 24 contests it has been chosen as underdogs in this season.
• San Diego is 11-7 this season when entering a game favored by -118 or more on the moneyline.
• This year, the Giants have won eight of 20 games when listed as at least +100 or worse on the moneyline.
• Based on this contest's moneyline, the Padres' implied win probability is 54.1%.
• The Giants have an implied victory probability of 50% according to the moneyline set by oddsmakers for this matchup.

Padres vs. Giants: Betting the Spread & Total

• The Padres have combined with opponents to hit the over on the total 15 times this season for a 15-17-2 record against the over/under.
• Games involving San Francisco have gone over the total set by sportsbooks in 14 of 35 chances this season.
• The Padres have collected a 19-15-0 record against the spread this season (covering 55.9% of the time).
• The Giants have posted a record of 15-20-0 against the spread this season.