Padres vs. White Sox Dunkel MLB Picks, Predictions and Prop Bets - May 1

The San Diego Padres host the Chicago White Sox to start a three-game series at Petco Park, with first pitch at 9:40 p.m. ET on Friday. German Marquez (3-1, 4.38 ERA) will start for the Padres, who are 19-11 this season and second in the NL West. Noah Schultz (1-1, 3.52 ERA) is the expected starter for the White Sox, who are 14-17 and third in the AL Central.

The White Sox (+126) take their show on the road to face the favored Padres (-150). The game has an over/under of 8.5 runs.

Padres vs. White Sox Odds, Game Time

• Game day: Friday, May 1, 2026
• Game time: 9:40 p.m. ET
• Location: San Diego, California
• Stadium: Petco Park
• Favorite: Padres (-150)
• Underdog: White Sox (+126)
• Over/under: 8.5

How to Watch Padres vs. White Sox

• TV Channel: SDPA and CHSN
• Live Stream: Fubo (Watch for free)

Bet now on FanDuel Sportsbook!

Padres vs. White Sox: Betting the Moneyline

• The Padres have won 11 of the 16 games they were favored on the moneyline this season (68.8%).
• Chicago has been pegged as an underdog in 27 games this year and has walked away with the win 12 times (44.4%) in those games.
• San Diego is 7-1 this season when entering a game favored by -150 or more on the moneyline.
• This year, the White Sox have won six of 14 games when listed as at least +126 or worse on the moneyline.
• The Padres have an implied moneyline win probability of 60% in this contest.
• The moneyline set for this matchup implies the White Sox have a 44.2% chance of walking away with the win.

Padres vs. White Sox: Betting the Spread & Total

• The Padres have played in 30 games with a set over/under, and have combined with their opponents to go over the total 14 times (14-14-2).
• So far this season, Chicago and its opponents have hit the over in 18 of its 31 games with a total.
• The Padres have covered 63.3% of their games this season, going 19-11-0 against the spread.
• The White Sox have posted a record of 16-15-0 against the spread this season.