Sabres vs. Blackhawks NHL Predictions, Picks and Odds - Nov. 21

Both the Buffalo Sabres and Chicago Blackhawks are coming off a loss, heading into their matchup at KeyBank Center on Friday at 7 p.m. ET. The bookmakers have made the Sabres solid favorites at -180 on the moneyline, and the Blackhawks are at +150.

Buffalo's last game was a 6-2 home loss to the Calgary Flames on Nov. 19. Mattias Samuelsson's two points (one goal and one assist) led the Sabres.

Chicago played at home in its last game on Nov. 20, and fell 3-2 against the Seattle Kraken. The Blackhawks were led in that matchup by Teuvo Teravainen (one goal and one assist) and Tyler Bertuzzi (one goal and one assist).

Ahead of watching this matchup, here is a glimpse at which club we think will come out on top in Friday's action on the ice.

Sabres vs. Blackhawks Predictions & Pick

Ahead of the upcoming contest between the Buffalo Sabres and Chicago Blackhawks, computer-calculated moneyline, over/under, and score predictions are below, sourced from Dunkel Index.

• Prediction: Blackhawks 3 - Sabres 1
• Pick OU: Under 6.5 (Dunkel projecting 4.03 goals)
  

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Sabres vs. Blackhawks Moneylines

Grab a peek below at the most recent moneylines for the Sabres-Blackhawks game.

• Favorite: Sabres (-180)
• Underdog: Blackhawks (+150)

Sabres Betting Insights

• The Sabres have won 33.3% of their games when favored on the moneyline this season (2-4).
• Buffalo has not played a game with moneyline odds shorter than -180.
• The Sabres' implied moneyline win probability is 64.3% in this game.
• Buffalo and its opponent have posted more than 6.5 goals in 11 of 20 games this season.

Blackhawks Betting Insights

• The Blackhawks have been made an underdog 19 times this season, and won 10, or 52.6%, of those games.
• Chicago has gone 3-3 when it's been set as an underdog of +150 or more by bookmakers this season.
• The moneyline set in this matchup implies a 40.0% chance of victory for the Blackhawks.
• Chicago has combined with its opponent to score more than 6.5 goals in seven of 20 games this season.

Sabres Key Stats

• Buffalo's 57 total goals (2.8 per game) make it the 26th-ranked scoring team in the NHL.
• Defensively, the Sabres are conceding 71 total goals (3.6 per game) to rank 26th in NHL action.
• Its -14 goal differential ranks 27th in the league.
• The 10 power-play goals the Sabres have scored this season (to rank 21st in the NHL) have come on 61 power-play chances.
• Buffalo's 16.39% power-play conversion rate ranks 23rd in the league.
• The three shorthanded goals the Sabres have scored this season rank fourth among NHL teams.
• Buffalo has a league-best 89.83% penalty-kill percentage.
• Buffalo wins 42.6% of its faceoffs (32nd in NHL).
• The Sabres connect on 10.2% of their shots (23rd in the league).

Blackhawks Key Stats

• Chicago has 66 goals this season (3.3 per game), 12th in the NHL.
• The Blackhawks' total of 51 goals allowed (2.6 per game) is third in the league.
• With a goal differential of +15, the team is second-best in the league in that category.
• The Blackhawks have 14 power-play goals (13th in NHL) on 58 chances.
• Chicago has the NHL's ninth-best power-play percentage (24.14%).
• This season, the Blackhawks have one shorthanded goal (15th in league).
• The 83.56% penalty-kill percentage of Chicago is seventh in the league.
• Chicago is 28th in faceoff win rate in the NHL (46.5%).
• The Blackhawks' 13.1% shooting percentage is second in the league.