Matthew Stafford vs. 49ers - NFL - Player Props, Lines and Trends

See what sportsbooks have posted for Matthew Stafford's player prop betting options in Thursday's NFL action, as he takes to the field at 8:35 p.m. ET broadcast on Netflix. Stafford and the Los Angeles Rams (0-0) travel to Melbourne, Australia to take the field against the San Francisco 49ers (0-0) at Melbourne Cricket Ground in Week 1.

Matthew Stafford Player Props

Stafford Passing Insights

• Stafford put up 276.9 passing yards per game last year, 14.4 yards more than Thursday's over/under.
• In 10 of 17 matchups last year, Stafford threw for more than 262.5 yards.
• Stafford's passing yards total per game of 276.9 last season was higher than his average prop bet total (252.2) by 24.7 yards.
• Stafford hit the over on his passing yards total in 10 games last season (66.7% of total opportunities).
• Stafford had a passing touchdown in all 17 games last season, with multiple passing TDs in 15 of them.
• Stafford threw at least one interception in five of 17 games last year, including multiple INTs twice.

Stafford Rushing Insights

• Thursday's rushing yards over/under for Stafford is 0.5. That is 0.4 more than his average of 0.1 last year.
• On six occasions last year (out of 17 total games, or 35.3%), Stafford had more than 0.5 rushing yards.
• Stafford rushed for 0.3 fewer yards per game last year than his average rushing yards over/under (0.4).
• Stafford hit the rushing yards over in five of 12 opportunities (41.7%) last season.
• Stafford did not find paydirt on the ground last year in 17 games.

San Francisco 49ers Rankings (2025)

• The 232.4 yards per game the 49ers gave up through the air last year made them the NFL's 25th-ranked pass defense.
• The 49ers' defense was 21st in the NFL last year, giving up 1.7 passing touchdowns per game.
• With six interceptions last year, the 49ers' defense was 29th in the league.

For more expert NFL prop picks and best bets, visit Dunkel Index Best NFL Player Props today.