Panthers vs. Bruins NHL Predictions, Picks and Odds - Oct. 21
21 October 2025

The Florida Panthers and Boston Bruins -- both coming off losses -- will play on Tuesday at 7:30 p.m. ET, at TD Garden in Boston. The Bruins are underdogs despite being the hosts, at +130, and the Panthers are -155.
Florida's most recent game was a 3-0 road loss to the Buffalo Sabres on Oct. 18. Daniil Tarasov had zero saves for the Panthers while allowing zero Sabres goals.
Boston played on the road its last time out on Oct. 19, and fell 3-2 against the Utah Mammoth. David Pastrnak's two points (two goals) in that matchup led the Bruins.
Get ready for this showdown with a look at who we predict will emerge with the victory in Tuesday's game.
Bet now on FanDuel Sportsbook!Panthers vs. Bruins Predictions & Pick
For the upcoming contest between the Florida Panthers and Boston Bruins, computer-derived moneyline, over/under, and score predictions are below, based on data from Dunkel Index.
- Prediction: Panthers 4 - Bruins 3
- Pick OU:
Over 5.5
(Dunkel projecting 7.08 goals)
Pick with the best in the business! Get free picks for every game, every week at the Dunkel Index.
Panthers vs. Bruins Moneylines
Grab a look below at the latest moneylines for the Panthers-Bruins matchup.
- Favorite: Panthers (-155)
- Underdog: Bruins (+130)
Panthers Betting Insights
- The Panthers are 3-3 this season when listed as a moneyline favorite.
- When it has played with moneyline odds of -155 or shorter, Florida is 3-1 (winning 75.0% of the time).
- Based on the moneyline in this contest, the Panthers' implied win probability is 60.8%.
- In two games this season, Florida and its opponent have combined for more than 5.5 goals.
Bruins Betting Insights
- The Bruins have been made an underdog five times this season, and won once.
- Boston has gone 1-4 when it's been set as an underdog of +130 or more by sportsbooks this season.
- The Bruins have a 43.5% chance to win this game based on the implied probability of the moneyline.
- Boston has combined with its opponent to score over 5.5 goals in three of seven games this season.
Panthers Key Stats
- Florida ranks 24th in the league with 15 goals scored (2.1 per game).
- The Panthers rank 23rd in goals against, conceding 20 total goals (2.9 per game) in NHL action.
- It has the league's 27th-ranked goal differential at -5.
- The six power-play goals the Panthers have recorded this season (on 31 power-play chances) are the third-most in the NHL.
- Florida's 19.35% power-play conversion rate ranks 16th in the league.
- The one shorthanded goal the Panthers have scored this season rank third among NHL teams.
- Florida has the league's 10th-best penalty-kill percentage (83.33%).
- Florida wins 47.4% of its faceoffs (24th in NHL).
- The Panthers shoot 7.5% as a team (30th in the league).
Bruins Key Stats
- Boston's 21 goals on the season (three per game) rank seventh in the NHL.
- The Bruins' total of 22 goals given up (3.1 per game) is 27th in the league.
- With a goal differential of -1, the team is 18th in the league.
- The Bruins have four power-play goals (11th in NHL) on 25 chances.
- Boston has the NHL's 20th-ranked power-play percentage (16%).
- The 90% penalty-kill percentage of Boston is sixth in the NHL.
- Boston wins 56.3% of faceoffs, second-best in the NHL.
- The Bruins' 11.5% shooting percentage is 12th in the league.
