Brewers vs. Pirates Dunkel MLB Picks, Predictions and Prop Bets - Sept. 17

Brandon Lowe brings a two-game homer streak into the Pittsburgh Pirates' game against the Milwaukee Brewers at 12:35 p.m. ET on Thursday, at PNC Park. Kyle Harrison (10-4, 3.98 ERA) will start for the Brewers, who are 95-57 this season and first in the NL Central. Wilber Dotel (1-5, 4.84 ERA) is the expected starter for the Pirates, who are 75-77 and third in the NL Central.

Despite playing away from home the Brewers are at -144 to win, compared to the Pirates at +119. The total for the Brewers-Pirates game is set at 8.5.

Brewers vs. Pirates Odds, Game Time

• Game day: Thursday, September 17, 2026
• Game time: 12:35 p.m. ET
• Location: Pittsburgh, Pennsylvania
• Stadium: PNC Park
• Favorite: Brewers (-144)
• Underdog: Pirates (+119)
• Over/under: 8.5

How to Watch Brewers vs. Pirates

• TV Channel: SportsNet PT and BREW
• Live Stream: Fubo (Watch for free)

Bet now on FanDuel Sportsbook!

Brewers vs. Pirates: Betting the Moneyline

• The Brewers have won 65.3% of the games this season when they were favored on the moneyline (77-41).
• Pittsburgh has been pegged as an underdog in 74 games this year and has walked away with the win 31 times (41.9%) in those games.
• Milwaukee has a record of 44-26, a 62.9% win rate, when favored by -144 or more by oddsmakers this season.
• The Pirates have a win-loss record of 11-17 when favored by +119 or worse by sportsbooks this year.
• The Brewers have an implied moneyline win probability of 59% in this matchup.
• The Pirates have an implied victory probability of 45.7% according to the moneyline set for this matchup.

Brewers vs. Pirates: Betting the Spread & Total

• In the 152 games in which bookmakers have set an over/under for the Brewers, they have combined with opponents to go over the total 67 times (67-79-6).
• Pittsburgh's games have gone over the total in 77 of its 152 chances.
• The Brewers have put together a 79-73-0 record against the spread this season (covering 52% of the time).
• The Pirates have an against the spread mark of 73-79-0 in 152 games with a line this season.