Brewers vs. Pirates Dunkel MLB Picks, Predictions and Prop Bets - Sept. 16

The Milwaukee Brewers and Pittsburgh Pirates square off on Wednesday at 6:40 p.m. ET, at PNC Park. Logan Henderson (10-3, 2.34 ERA) gets the start for the Brewers, who are 94-57 this season and first in the NL Central. Jared Jones (4-6, 4.10 ERA) is the expected starter for the Pirates, who are 75-76 and third in the NL Central.

Even though the Brewers are playing on the road at the Pirates, they are currently favored on the moneyline at -130, compared to the home team at +106. The game has an over/under of 7.5 runs.

Brewers vs. Pirates Odds, Game Time

• Game day: Wednesday, September 16, 2026
• Game time: 6:40 p.m. ET
• Location: Pittsburgh, Pennsylvania
• Stadium: PNC Park
• Favorite: Brewers (-130)
• Underdog: Pirates (+106)
• Over/under: 7.5

How to Watch Brewers vs. Pirates

• TV Channel: SportsNet PT and BREW
• Live Stream: Fubo (Watch for free)

Bet now on FanDuel Sportsbook!

Brewers vs. Pirates: Betting the Moneyline

• The Brewers have gone 76-41 in games they were listed as the moneyline favorite (winning 65% of those games).
• Pittsburgh has been victorious in 31, or 42.5%, of the 73 contests it has been chosen as underdogs in this season.
• This season Milwaukee has won 62 of its 93 games, or 66.7%, when favored by at least -130 on the moneyline.
• This season, the Pirates have been victorious 19 times in 46 chances when named as an underdog of at least +106 or worse on the moneyline.
• The Brewers have a 56.5% chance to win this matchup based on the moneyline's implied probability.
• The moneyline set for this matchup implies the Pirates have a 48.5% chance of walking away with the win.

Brewers vs. Pirates: Betting the Spread & Total

• The Brewers have combined with opponents to go over the total 66 times this season for a 66-79-6 record against the over/under.
• Games involving Pittsburgh have gone over the total set by bookmakers in 76 of 151 chances this season.
• The Brewers have covered 52.3% of their games this season, going 79-72-0 ATS.
• The Pirates have an against the spread record of 72-79-0 in 151 games with a line this season.