Dodgers vs. Padres Dunkel MLB Picks, Predictions and Prop Bets - Sept. 23

The Los Angeles Dodgers ride a five-game win streak into a home contest versus the San Diego Padres at 10:10 p.m. ET on Wednesday. Yoshinobu Yamamoto (14-8, 2.51 ERA) will start for the Dodgers, who are 97-60 this season and first in the NL West. Robbie Ray (13-8, 3.60 ERA) is expected to start for the Padres, who are 87-70 and second in the NL West.

The oddsmakers have spoken, making the Dodgers (-225) a moderate moneyline favorite to defeat the Padres (+181) at home. The over/under in this contest is 8.

Dodgers vs. Padres Odds, Game Time

• Game day: Wednesday, September 23, 2026
• Game time: 10:10 p.m. ET
• Location: Los Angeles, California
• Stadium: Dodger Stadium
• Favorite: Dodgers (-225)
• Underdog: Padres (+181)
• Over/under: 8

How to Watch Dodgers vs. Padres

• TV Channel: SportsNet LA and SDPA
• Live Stream: Fubo (Watch for free)

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Dodgers vs. Padres: Betting the Moneyline

• The Dodgers have been favored on the moneyline 150 total times this season. They've gone 95-55 in those games.
• San Diego has won in 36, or 47.4%, of the 76 contests it has been named as odds-on underdogs in this year.
• Los Angeles has a record of 34-15, a 69.4% win rate, when favored by -225 or more by bookmakers this season.
• The Padres have a win-loss record of 1-4 when favored by +181 or worse by oddsmakers this year.
• Based on this game's moneyline, the Dodgers' implied win probability is 69.2%.
• The Padres have an implied victory probability of 35.6% according to the moneyline set by oddsmakers for this matchup.

Dodgers vs. Padres: Betting the Spread & Total

• In the 157 games in which oddsmakers have set an over/under for the Dodgers, they have combined with opponents to go over the total 72 times (72-83-2).
• So far this season, San Diego and its opponents have hit the over in 74 of its 157 games with a total.
• The Dodgers have covered 44.6% of their games this season, going 70-87-0 against the spread.
• The Padres are 88-69-0 against the spread in their 157 games with a line set by sportsbooks this season.