Kentucky vs. Loyola (MD) Dunkel Predictions & Vegas Odds - Nov. 21

The No. 12 Kentucky Wildcats (3-2) host the Loyola (MD) Greyhounds (2-4) at Rupp Arena, tipping off at 7 p.m. ET on Friday, November 21, 2025. The Greyhounds are 35.5-point underdogs in the game. The matchup's over/under is set at 155.5.

In its last time out, Kentucky lost 83-66 to Michigan State on Tuesday. Otega Oweh scored a team-best 12 points for Kentucky in the loss. Loyola (MD)'s most recent contest on Wednesday ended in a 92-78 loss to Duquesne. Jacob Theodosiou recorded 21 points, three rebounds and four assists for Loyola (MD).

Kentucky vs. Loyola (MD) Odds and Game Time

• When: Friday, November 21, 2025 at 7 p.m. ET
• Where: Rupp Arena in Lexington, Kentucky
• Spread favorite: Kentucky -35.5
• Moneyline favorite: Kentucky -10000
• Moneyline underdog: Loyola (MD) +3300
• Over/Under: 155.5 points

How to watch Kentucky vs. Loyola (MD)

• TV Channel: SEC Network+
• Check out the rest of our Dunkel Index NCAA Basketball Picks!

Betting the Over/Under: Kentucky vs. Loyola (MD)

• Kentucky and its opponents have combined to score more than 155.5 points in a game twice this season.
• There have been two games featuring Loyola (MD) this season with more combined points than Friday's point total of 155.5.
• Together, the two teams combine for 162.4 points per game, 6.9 points more than the total of 155.5 for this game.
• The 140.6 points per game these two teams surrender to opponents on average this season are 14.9 fewer than the 155.5 over/under in this contest.
• On average, Kentucky has seen a 155.8-point over/under in its games this season, 0.3 more points than the over/under in this contest.
• The over/under for this matchup is 8.3 points more than the average over/under in Loyola (MD)'s games this season (147.2 points).

Betting the Spread: Kentucky vs. Loyola (MD)

• Kentucky has covered the spread twice this year.
• This season, the Wildcats won ATS in their only game as a favorite of 35.5 points or more.
• Loyola (MD) is 3-2-0 against the spread this season.
• Kentucky has two wins against the spread, and is 3-0 overall, at home this year.
• Kentucky is unbeaten ATS (1-0) as a 35.5-point favorite or more at home.

Betting the Moneyline: Kentucky vs. Loyola (MD)

• Kentucky has entered the game as moneyline favorites three times this season and won twice.
• The Wildcats have played as a favorite of -10000 or more twice this season and won both games.
• Oddsmakers have implied with the moneyline set for this matchup that Kentucky has a 99% chance to win.
• Loyola (MD) has been moneyline underdogs in three games this season, however, it has failed to come away with a win in any of those games.
• Oddsmakers have given the Greyhounds the worst odds of winning they have seen this season with a +3300 moneyline listed for this contest.
• The moneyline set for this matchup implies Loyola (MD) has a 2.9% chance of coming away with a victory in the contest.