Chiefs vs. Colts Week 2 Dunkel NFL Picks, Predictions and Odds

The Kansas City Chiefs (1-0) are favored by 5.5 points against the Indianapolis Colts (0-1) on September 20, 2026, starting at 8:20 p.m. ET, airing on NBC/Peacock. The expected point total for the game is 46.5.

The Chiefs put up 21.3 points per game on offense last season (21st in NFL), and they gave up 19.3 points per game (sixth) on the other side of the ball. The Colts totaled 345.9 yards per game on offense last season (ninth in NFL), and they gave up 349.8 yards per game (23rd) on the defensive side of the ball.

Chiefs vs. Colts Odds and Game Time

• Date: Sunday, September 20, 2026
• Time: 8:20 p.m. ET
• City: Kansas City, Missouri
• Venue: GEHA Field at Arrowhead Stadium
• Total: 46.5 points
• Spread: Chiefs -5.5
• Moneyline: Chiefs (-265), Colts (+215)

How to watch Chiefs vs. Colts

• TV Channel: NBC/Peacock

Betting the Over/Under: Chiefs vs. Colts

• Chiefs games last season featured more combined points than this contest's total of 46.5 points six times.
• Chiefs games hit the over four out of 17 times last season.
• The Colts combined with their opponent to score more than 46.5 points in 11 of 17 games last season.
• In Indianapolis games last season, combined scoring went over the point total nine times.
• These two teams racked up a combined 48.7 points per game last season, 2.2 more points than this matchup's total.
• These two teams gave up a combined 43.5 points per game last year, 3.0 fewer points than the over/under for this contest.

Betting the Spread: Chiefs vs. Colts

• Kansas City compiled a 6-11-0 ATS record last year.
• Kansas City covered the spread when playing as at least 5.5-point favorites in three of three opportunities last season.
• The Colts went 9-8-0 ATS last year.
• Indianapolis was an underdog by 5.5 points or more two times last season, and covered the spread in both.
• At home last season, the Chiefs were 5-4 against the spread and 5-4 overall.
• At home last year, Kansas City was unbeaten ATS (2-0) as 5.5-point favorites or greater.
• On the road last season, the Colts were 2-6 overall and 5-3 against the spread.
• On the road, Indianapolis was unbeaten ATS (2-0) as 5.5-point underdogs or more.

Betting the Moneyline: Chiefs vs. Colts

• Kansas City was favored on the moneyline 14 total times last season. They finished 5-9 in those games.
• The Colts won two of the eight games they played as underdogs last season.
• Kansas City went 3-1 when playing as a moneyline favorite with odds of -265 or shorter (75%).
• Last season, Indianapolis was at least a +215 underdog on the moneyline two times, losing each of those contests.
• Based on this contest's moneyline, the Chiefs' implied win probability is 72.6%.

Dunkel Prediction for Chiefs vs. Colts

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