Astros vs. Royals Dunkel MLB Picks, Predictions and Prop Bets - Sept. 16

The Kansas City Royals hope to stop their three-game losing run versus the Houston Astros, at 8:10 p.m. ET on Wednesday. Cristian Javier (2-5, 5.50 ERA) gets the start for the Astros, who are 76-75 this season and first in the AL West. Daniel Lynch (5-5, 3.52 ERA) is starting for the Royals, who are 66-85 and fifth in the AL Central.

The Royals (+134) are on the road versus the favored Astros (-163). The game's total is set at 9.

Astros vs. Royals Odds, Game Time

• Game day: Wednesday, September 16, 2026
• Game time: 8:10 p.m. ET
• Location: Houston, Texas
• Stadium: Daikin Park
• Favorite: Astros (-163)
• Underdog: Royals (+134)
• Over/under: 9

How to Watch Astros vs. Royals

• TV Channel: SCHN and ROYL
• Live Stream: Fubo (Watch for free)

Bet now on FanDuel Sportsbook!

Astros vs. Royals: Betting the Moneyline

• The Astros have gone 32-31 in games they were favored on the moneyline (winning 50.8% of those games).
• Kansas City has been underdogs in 97 games this season and has come away with the win 39 times (40.2%) in those contests.
• Houston has a record of 7-10, a 41.2% win rate, when favored by -163 or more by oddsmakers this season.
• This year, the Royals have won 10 of 29 games when listed as at least +134 or worse on the moneyline.
• The implied moneyline probablility for this matchup gives the Astros a 62% chance to win.
• The moneyline set for this matchup implies the Royals have a 42.7% chance of walking away with the win.

Astros vs. Royals: Betting the Spread & Total

• The Astros have played in 151 games with an over/under set, and have combined with their opponents to go over the total 74 times (74-68-9).
• Kansas City and its opponents have gone over the total this season in 66 of its 151 opportunities.
• The Astros have a 79-72-0 record against the spread this season (covering 52.3% of the time).
• The Royals are 74-77-0 against the spread in their 151 games with a line set by sportsbooks this season.