Duke vs. Clemson Dunkel Predictions & Vegas Odds - ACC Tournament

The No. 1 seed Duke Blue Devils (30-2, 17-1 ACC) and the No. 5 seed Clemson Tigers (24-9, 12-6 ACC) meet in the ACC Tournament Friday at Spectrum Center, beginning at 9:30 p.m. ET on ESPN2. Duke is favored by 10.5 points. Both teams are looking to take another step toward a conference title and an automatic spot in the NCAA Tournament bracket. The matchup has an over/under of 132.5.

Duke won its last matchup 80-79 against Florida State on Thursday. Isaiah Evans recorded 32 points, six rebounds and three assists for Duke. Clemson heads into this matchup after an 80-79 victory over North Carolina on Thursday. Nick Davidson scored a team-best 17 points for Clemson in the win.

Duke vs. Clemson Odds and Game Time

• When: Friday, March 13, 2026 at 9:30 p.m. ET
• Where: Spectrum Center in Charlotte, North Carolina
• Spread favorite: Duke -10.5
• Moneyline favorite: Duke -649
• Moneyline underdog: Clemson +447
• Over/Under: 132.5 points

How to watch Duke vs. Clemson

• TV Channel: ESPN2
• Check out the rest of our Dunkel Index NCAA Basketball Picks!

Betting the Over/Under: Duke vs. Clemson

• This season, Duke's games have hit the over on this matchup's 132.5-point over/under 23 times.
• There have been 22 Clemson games that ended with a combined score over 132.5 points this season.
• Together, the two teams combine for 157.3 points per game, 24.8 points more than the total of 132.5 for this matchup.
• The 129.5 points per game these two teams surrender to opponents combined this season are three less than the 132.5-point over/under in this contest.
• Duke has a 145.8 average over/under in its games this season, 13.3 more points than the over/under in this contest.
• The over/under for this game is 8.6 points lower than the average over/under in Clemson's games this season (141.1 points).

Betting the Spread: Duke vs. Clemson

• Duke has played 32 games, with 18 wins against the spread.
• So far this season, the Blue Devils have been installed as favorites by a 10.5-point margin or more 23 times and are 12-11 ATS in those games.
• Clemson is 15-17-1 against the spread this year.
• The Tigers have been underdogs by 10.5 points or more two times this season and covered the spread once.
• At home this season, Duke is 15-0 overall and 7-8 against the spread.
• Duke is 5-7 ATS as a 10.5-point favorite or greater at home.
• In away games, Clemson is 6-5 against the spread, and 6-5 overall.

Betting the Moneyline: Duke vs. Clemson

• This season, Duke has been moneyline favorites 28 times and won 26, or 92.9%, of those games.
• The Blue Devils are undefeated in 19 games this season when favored by -649 or more on the moneyline.
• Oddsmakers have implied with the moneyline set for this matchup that Duke has a 86.6% chance to win.
• Clemson has won in one of the five contests it has been named as the moneyline underdog this year.
• The Tigers have played as an underdog of +447 or more just one time this year and came away with a loss in that game.
• The moneyline set for this matchup implies Clemson has an 18.3% chance of coming away with a victory in the contest.