Pistons vs. 76ers Dunkel NBA Picks, Predictions and Odds - Nov. 4

Two streaking squads square off when the Detroit Pistons (6-1) host the Philadelphia 76ers (7-1) on November 4, 2026. The Pistons are putting their three-game winning streak on the line versus the 76ers, who have won four in a row.

Detroit is a moderate 2.5-point favorite against Philadelphia when the Pistons square off against the 76ers on Wednesday. The over/under is 219.5 points for the game.

Pistons vs. 76ers Odds and Game Time

• Game day: Wednesday, November 4, 2026
• Game time: 7 p.m. ET
• Location: Detroit, Michigan
• Arena: Little Caesars Arena
• Total: 219.5 points
• Spread: Pistons -2.5
• Moneyline: Pistons (-130), 76ers (+110)

How to watch Pistons vs. 76ers

• TV Channel: ESPN, NBCS-PH, PCK-PHI

Betting the Over/Under: Pistons vs. 76ers

• Pistons games have gone over 219.5 points two times this season (over seven outings).
• The 76ers have played four games this season that finished with a combined score above 219.5 points.
• These teams rack up a combined 222.8 points per game, 3.3 more points than this matchup's point total.
• Combined, these teams surrender 205.4 points per game, 14.1 fewer points than this matchup's total.

Betting the Spread: Pistons vs. 76ers

• Detroit is 6-1-0 ATS this season.
• The Pistons have covered the spread three times this season (3-0 ATS) when playing as at least 2.5-point favorites.
• The 76ers are 5-3-0 ATS this season.
• Philadelphia has won its only game this year when playing as at least 2.5-point underdogs.
• At home, as a 2.5-point favorite or more, Detroit is unbeaten ATS (1-0).
• The 76ers are 3-0 overall, with two wins against the spread, away from home.
• Philadelphia is winless ATS (0-1) as 2.5-point underdogs or more away from home.

Betting the Moneyline: Pistons vs. 76ers

• The Pistons have yet to lose as the moneyline favorite this season, going 5-0.
• The 76ers have entered the game as underdogs three times this season and won twice.
• Detroit has won all four games it played as a moneyline favorite with odds of -130 or shorter.
• Philadelphia has been at least a +110 moneyline underdog two times this season but won all of those games.
• The Pistons have an implied moneyline win probability of 56.5% in this matchup.

Dunkel Index Prediction for Pistons vs. 76ers

• Pick ATS: 76ers (+ 2.5)
• Pick OU: Under (219.5)
  
• Prediction: 76ers 107 - Pistons 106
• Check out the rest of our Dunkel Index NBA Picks!