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Guardians vs. Mariners Dunkel MLB Picks, Predictions and Prop Bets - June 26

26 June 2026 By Data Skrive

The Cleveland Guardians host the Seattle Mariners to start a three-game series at Progressive Field, with first pitch at 7:10 p.m. ET on Friday. Joey Cantillo (6-3, 4.05 ERA) gets the start for the Guardians, who are 42-39 this season and second in the AL Central. Luis Castillo (2-6, 5.22 ERA) is the expected starter for the Mariners, who are 41-41 and first in the AL West.

With moneyline odds of -115 for the Guardians and -107 for the Mariners, this could be a close contest. The contest has a total set at 7.5.

Guardians vs. Mariners Odds, Game Time

  • Game day: Friday, June 26, 2026
  • Game time: 7:10 p.m. ET
  • Location: Cleveland, Ohio
  • Stadium: Progressive Field
  • Favorite: Guardians (-115)
  • Underdog: Mariners (-107)
  • Over/under: 7.5

How to Watch Guardians vs. Mariners

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Guardians vs. Mariners: Betting the Moneyline

  • The Guardians have won 51.2% of the games this season when they were the moneyline favorite (22-21).
  • Seattle has won in two of the seven contests it has been named as odds-on underdogs in this year.
  • This season Cleveland has won 21 of its 41 games, or 51.2%, when favored by at least -115 on the moneyline.
  • This year, the Mariners have won two of seven games when listed as at least -107 or worse on the moneyline.
  • The Guardians have a 53.5% chance to win this game based on the moneyline's implied probability.
  • The moneyline set for this matchup implies the Mariners have a 51.7% chance of coming away with a victory in the contest.

Guardians vs. Mariners: Betting the Spread & Total

  • The Guardians have had an over/under set by bookmakers 81 times, and have combined with opponents to go over the total in 39 of those games (39-42-0).
  • Games involving Seattle have gone over the total set by oddsmakers in 39 of 82 chances this season.
  • The Guardians are 41-40-0 against the spread this season.
  • The Mariners are 30-52-0 against the spread in their 82 games with a line set by sportsbooks this season.
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