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Cubs vs. Nationals Dunkel MLB Picks, Predictions and Prop Bets - March 26

25 March 2026 By Data Skrive

The Chicago Cubs are facing the Washington Nationals to begin the MLB season on Thursday. First pitch is at 2:20 p.m. ET at Wrigley Field. Matthew Boyd gets the start for the Cubs, and Cade Cavalli is expected to start for the Nationals.

At home, the Cubs are favored to win on the moneyline (-228) over the Nationals (+188). The contest has an over/under set at 7.

Cubs vs. Nationals Odds, Game Time

  • Game day: Thursday, March 26, 2026
  • Game time: 2:20 p.m. ET
  • Location: Chicago, Illinois
  • Stadium: Wrigley Field
  • Favorite: Cubs (-228)
  • Underdog: Nationals (+188)
  • Over/under: 7

How to Watch Cubs vs. Nationals

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Cubs vs. Nationals: Betting the Moneyline

  • The Cubs put together a 77-43 record in games they were listed as the moneyline favorite last season (winning 64.2% of those games).
  • Washington came away with 59 wins in the 140 contests it was listed as the underdogs in last season.
  • In games it played as a moneyline favorite with odds of -228 or shorter last year, Chicago had a record of 11-3 (78.6%).
  • Last year, Washington won eight of 21 games when listed as at least +188 on the moneyline.
  • Based on this matchup's moneyline, the Cubs' implied win probability is 69.5%.
  • Sportsbooks have implied with the moneyline set for this matchup that the Nationals have a 34.7% chance of pulling out a win.

Cubs vs. Nationals: Betting the Spread & Total

  • The Cubs combined with their opponents to go over the total 78 times last season for a 78-82-10 record against the over/under.
  • Washington and its opponents hit the over in 80 of its 161 games with a total last season.
  • The Cubs covered 47.6% of their games last season, going 81-89-0 ATS.
  • The Nationals posted a record of 79-82-0 against the spread last season.
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