Bills vs. Steelers Week 13 Dunkel NFL Picks, Predictions and Odds

The Buffalo Bills (7-4) are favored by three points against the Pittsburgh Steelers (6-5) on November 30, 2025, starting at 4:25 p.m. ET, airing on CBS. The total for this one is set at 44.5 points.

The Bills own the 17th-ranked defense this year (22.9 points allowed per game), and they've been more effective on offense, ranking fifth-best with 28.3 points per game. The Steelers have not been getting things done on defense, ranking fifth-worst with 364.5 total yards given up per game. They have been better offensively, regstering 292.2 total yards per contest (27th-ranked).

Bills vs. Steelers Odds and Game Time

• Date: Sunday, November 30, 2025
• Time: 4:25 p.m. ET
• City: Pittsburgh, Pennsylvania
• Venue: Acrisure Stadium
• Total: 44.5 points
• Spread: Bills -3
• Moneyline: Bills (-166), Steelers (+140)

How to watch Bills vs. Steelers

• TV Channel: MyNetworkTV (KELO – Sioux Falls, SD)
• Live Stream: Fubo

Betting the Over/Under: Bills vs. Steelers

• The Bills and their opponents have gone over 44.5 combined points six times this season.
• Buffalo and its opponent have combined to go over the point total five out of 11 times this season.
• The Steelers have combined with their opponent to score more than 44.5 points in eight of 11 games this season.
• In Pittsburgh's 11 contests this year, the combined scoring has gone over the point total six times.
• The teams combine to score 53.2 points per game, 8.7 more points than this matchup's over/under.
• Combined, these teams allow 46.8 points per game, 2.3 more points than this matchup's over/under.

Betting the Spread: Bills vs. Steelers

• Buffalo has won five games against the spread this season, while failing to cover six times.
• Buffalo is 3-6 ATS this season when playing as at least 3-point favorites.
• The Steelers have won five games against the spread this year, failing to cover six times.
• Pittsburgh has covered the spread once this year (1-1 ATS) when playing as at least 3-point underdogs.
• The Steelers are 4-2 overall, and 4-2 against the spread, at home.
• Pittsburgh is unbeaten ATS (1-0) as 3-point underdogs or more at home.
• On the road, the Bills have two wins against the spread and are 2-3 overall.
• On the road, Buffalo has two wins ATS (2-3) as 3-point favorites or more.

Betting the Moneyline: Bills vs. Steelers

• Buffalo has won five of the nine games it was listed as the moneyline favorite this season (55.6%).
• The Steelers have entered the game as underdogs five times this season and won twice.
• Buffalo is 5-4 (winning 55.6% of its games) when it have played as a moneyline favorite of -166 or shorter.
• Pittsburgh has entered two games this season as the underdog by +140 or more and is 1-1 in those contests.
• The implied moneyline probability for this matchup gives the Bills a 62.4% chance to win.

Dunkel Prediction for Bills vs. Steelers

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