Bills vs. Eagles Week 17 Dunkel NFL Picks, Predictions and Odds

Having taken four straight, the Buffalo Bills (11-4) will face the Philadelphia Eagles (10-5). The Bills are the favorites, expected to win by at least a field goal but less than a touchdown (currently -3). The total for this one is set at 45.5 points.

The Bills rank 15th in scoring defense this season (22.9 points allowed per game), but they've been shining on the other side of the ball, ranking third-best in the NFL with 28.9 points per game. The Eagles have been thriving on defense, surrendering just 19.3 points per game (third-best). Offensively, they rank 16th by compiling 23.3 points per game.

Bills vs. Eagles Odds and Game Time

• Date: Sunday, December 28, 2025
• Time: 4:25 p.m. ET
• City: Orchard Park, New York
• Venue: Highmark Stadium
• Total: 45.5 points
• Spread: Bills -3
• Moneyline: Bills (-170), Eagles (+142)

How to watch Bills vs. Eagles

• TV Channel: FOX Net (Minot-Bismarck, ND)
• Live Stream: Fubo

Betting the Over/Under: Bills vs. Eagles

• The Bills and their opponents have scored more than 45.5 points in eight of 15 games this season.
• Buffalo games have gone over the point total eight out of 15 times this season.
• Eagles games this season have had a combined scoring total higher than 45.5 points in six of 15 outings.
• In Philadelphia's 15 contests this season, the combined scoring has gone over the point total six times.
• These two teams rack up 52.2 points per game between them, 6.7 more than this game's point total.
• Combined, these teams allow 42.2 points per game, 3.3 fewer points than this matchup's over/under.

Betting the Spread: Bills vs. Eagles

• Buffalo has compiled a 7-8-0 ATS record so far this year.
• Buffalo has covered the spread four times this season (4-8 ATS) when playing as at least 3-point favorites.
• The Eagles have won nine games against the spread this year, failing to cover six times.
• At home this season, the Bills are 3-4 against the spread and 6-1 overall.
• At home, Buffalo has one win ATS (1-4) as 3-point favorites or greater.
• The Eagles are 5-3 against the spread, and 5-3 overall, on the road.

Betting the Moneyline: Bills vs. Eagles

• Buffalo has won nine of the 13 games it was listed as the moneyline favorite this season (69.2%).
• The Eagles won the only game they've played as the underdog this season.
• In games it has played as a moneyline favorite with odds of -170 or shorter, Buffalo has a 7-4 record (winning 63.6% of its games).
• Philadelphia has not entered a game this season with longer moneyline odds than +142.
• Based on this contest's moneyline, the Bills have an implied win probability of 63.0%.

Dunkel Prediction for Bills vs. Eagles

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