Alabama vs. LSU Dunkel NCAA Football Picks, Predictions and Odds - Nov. 8

The No. 4 Alabama Crimson Tide (7-1) are double-digit, 10.5-point favorites at home at Bryant-Denny Stadium against the LSU Tigers (5-3) on Saturday, November 8, 2025. Both teams have stout defenses, with the Crimson Tide 19th in points per game allowed, and the Tigers 20th.

Facing the South Carolina Gamecocks in their last game, the Crimson Tide won 29-22.

In their most recent contest, the Tigers lost versus the Texas A&M Aggies, 49-25.

Alabama vs. LSU Predictions

For the upcoming game between the Alabama Crimson Tide and LSU Tigers, computer-calculated against-the-spread, over/under, and score predictions are below, per Dunkel Index.

• Pick ATS: Crimson Tide (- 10.5)
• Pick OU: Over (49.5)
  
• Prediction: Crimson Tide 34 - Tigers 20

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Alabama vs. LSU Moneylines

Snag a peek below at the most up-to-date moneylines for the Crimson Tide-Tigers matchup.

• Alabama Moneyline: -412
• LSU Moneyline: +318

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Alabama Betting Insights

• Alabama has won six of the seven games it was favored on the moneyline this season (85.7%).
• Alabama has a 4-1 record (winning 80% of its games) when playing as a moneyline favorite of -412 or shorter.
• The Crimson Tide and their opponents have scored more than 49.5 points in five of eight games this season.
• The average point total in Crimson Tide games this year is 51.8, 2.3 more than this matchup's over/under.
• The Crimson Tide are the 43rd-highest scoring team in college football this year. The Tigers have scored the 98th-most points.

LSU Betting Insights

• This season, LSU has won one out of the four games in which it has been the underdog.
• LSU has not entered a game this season with longer moneyline odds than +318.
• LSU has played three games this season that ended with a combined score over 49.5 points.
• LSU has a 51.6-point average over/under in their contests this season, 2.1 more points than this game's total.

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Key Stats for Alabama vs. LSU

• Over their last four meetings, Alabama has totaled three wins against LSU.
• In their last four meetings, each team has covered two times with those games eclipsing the point total on two occasions.
• The Crimson Tide rank 50th in total offense this year (410.5 yards per game), but they've been thriving on the defensive side of the ball, ranking 22nd-best in the FBS with 410.5 yards allowed per game.
• Alabama sports the 30th-ranked offense this year (34.4 points per game), and has been better on defense, ranking 19th-best with only 18.3 points allowed per game.
• The Tigers rank 94th with 355.3 total yards per contest on offense, and they rank 35th with 325.9 total yards ceded per contest on defense.
• LSU has been dominant on the defensive side of the ball, surrendering just 18.9 points per game (20th-best). On offense, it ranks 83rd by racking up 25.5 points per game.