Nationals vs. Padres Dunkel MLB Picks, Predictions and Prop Bets - May 29

The San Diego Padres hope to stop their four-game losing run versus the Washington Nationals, at 6:45 p.m. ET on Friday. Paxton Schultz (0-2, 5.30 ERA) gets the start for the Nationals, who are 29-28 this season and third in the NL East. Lucas Giolito (2-0, 2.70 ERA) is expected to start for the Padres, who are 31-24 and third in the NL West.

Oddsmakers expect a close matchup between the Nationals (-110 to win) and the Padres (-110). The over/under in this contest is set at 9.

Nationals vs. Padres Odds, Game Time

• Game day: Friday, May 29, 2026
• Game time: 6:45 p.m. ET
• Location: Washington D.C.
• Stadium: Nationals Park
• Favorite: Nationals (-110)
• Underdog: Padres (-110)
• Over/under: 9

How to Watch Nationals vs. Padres

• TV Channel: NATS and SDPA
• Live Stream: Fubo (Watch for free)

Bet now on FanDuel Sportsbook!

Nationals vs. Padres: Betting the Moneyline

• The Nationals have been the moneyline favorite only two other times so far this season, and they split the two games.
• San Diego has come away with 14 wins in the 26 contests it has been listed as the underdogs in this season.
• Washington has played as favorites of -110 or more twice this season and split those games.
• This season, the Padres have come away with a win 15 times in 27 chances when named as an underdog of at least -110 or longer on the moneyline.
• The Nationals have an implied moneyline win probability of 52.4% in this matchup.
• The moneyline set for this matchup implies the Padres have a 52.4% chance of walking away with the win.

Nationals vs. Padres: Betting the Spread & Total

• The Nationals have had an over/under set by bookmakers 57 times, and have combined with opponents to go over the total in 35 of those games (35-18-4).
• San Diego and its opponents have hit the over in 22 of its 55 games with a total this season.
• The Nationals have put together a 37-20-0 record against the spread this season.
• The Padres have posted a record of 31-24-0 against the spread this season.