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Cardinals vs. Nationals Dunkel MLB Picks, Predictions and Prop Bets - April 6

06 April 2026 By Data Skrive

The Washington Nationals bring a five-game losing streak into a matchup versus the St. Louis Cardinals, at 6:45 p.m. ET on Monday. Andre Pallante (1-0, 0.00 ERA) gets the start for the Cardinals, who are 5-4 this season and fourth in the NL Central. Zack Littell (0-1, 5.40 ERA) is starting for the Nationals, who are 3-6 and fifth in the NL East.

The moneyline odds for the Cardinals (-118) versus the Nationals (-102) are tight. The game has an over/under set at 8 runs.

Cardinals vs. Nationals Odds, Game Time

  • Game day: Monday, April 6, 2026
  • Game time: 6:45 p.m. ET
  • Location: Washington D.C.
  • Stadium: Nationals Park
  • Favorite: Cardinals (-118)
  • Underdog: Nationals (-102)
  • Over/under: 8

How to Watch Cardinals vs. Nationals

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Cardinals vs. Nationals: Betting the Moneyline

  • The Cardinals are playing as the moneyline favorite for the first time this season.
  • Washington has been victorious in three of the nine contests it has been chosen as underdogs in this season.
  • St. Louis has not entered a game this season as bigger favorites on the moneyline than the -118 odds on them winning this game.
  • This year, the Nationals have won three of nine games when listed as at least -102 or worse on the moneyline.
  • Based on this game's moneyline, the Cardinals' implied win probability is 54.1%.
  • The Nationals have an implied victory probability of 50.5% according to the moneyline set by oddsmakers for this matchup.

Cardinals vs. Nationals: Betting the Spread & Total

  • The Cardinals have had an over/under set by oddsmakers nine times, and have combined with opponents to go over the total in four of those games (4-4-1).
  • Washington and its opponents have hit the over in seven of its nine games with a total this season.
  • The Cardinals have put together a 5-4-0 record against the spread this season (covering 55.6% of the time).
  • The Nationals are 5-4-0 against the spread in their nine games that had a posted line this season.
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