Cardinals vs. Pirates Dunkel MLB Picks, Predictions and Prop Bets - May 20

The Pittsburgh Pirates carry a four-game losing streak into a home contest versus the St. Louis Cardinals, at 7:45 p.m. ET on Wednesday. Michael McGreevy (3-2, 2.10 ERA) will start for the Cardinals, who are 28-19 this season and second in the NL Central. Carmen Mlodzinski (3-3, 4.40 ERA) is expected to start for the Pirates, who are 24-24 and fifth in the NL Central.

Per the moneyline, the matchup between the Cardinals (-119) and Pirates (-101) looks like a close one. The over/under for this contest is set at 7.5.

Cardinals vs. Pirates Odds, Game Time

• Game day: Wednesday, May 20, 2026
• Game time: 7:45 p.m. ET
• Location: St. Louis, Missouri
• Stadium: Busch Stadium
• Favorite: Cardinals (-119)
• Underdog: Pirates (-101)
• Over/under: 7.5

How to Watch Cardinals vs. Pirates

• TV Channel: CARD and SportsNet PT
• Live Stream: Fubo (Watch for free)

Bet now on FanDuel Sportsbook!

Cardinals vs. Pirates: Betting the Moneyline

• The Cardinals have won four of the seven games they were favored on the moneyline this season (57.1%).
• Pittsburgh has won in six, or 31.6%, of the 19 contests it has been named as odds-on underdogs in this year.
• St. Louis has played as favorites of -119 or more twice this season and split those games.
• The Pirates have a win-loss record of 5-10 when favored by -101 or worse by sportsbooks this year.
• Based on this matchup's moneyline, the Cardinals have an implied win probability of 54.3%.
• The Pirates have an implied victory probability of 50.2% according to the moneyline set for this matchup.

Cardinals vs. Pirates: Betting the Spread & Total

• The Cardinals have combined with opponents to hit the over on the total 19 times this season for a 19-23-5 record against the over/under.
• So far this season, Pittsburgh and its opponents have hit the over in 26 of its 48 games with a total.
• The Cardinals have gone 30-17-0 ATS this season.
• The Pirates have an against the spread record of 24-24-0 in 48 games with a line this season.