Cardinals vs. Orioles Dunkel MLB Picks, Predictions and Prop Bets - Aug. 25

The St. Louis Cardinals and Baltimore Orioles clash on Tuesday at 7:45 p.m. ET, beginning a three-game series at Busch Stadium. Matthew Liberatore (5-11, 5.04 ERA) gets the start for the Cardinals, who are 66-66 this season and third in the NL Central. Chris Bassitt (4-4, 5.08 ERA) is expected to start for the Orioles, who are 63-68 and fifth in the AL East.

At home, the Cardinals are favored to win on the moneyline (-128) over the Orioles (+113). The game's over/under is set at 8.5.

Cardinals vs. Orioles Odds, Game Time

• Game day: Tuesday, August 25, 2026
• Game time: 7:45 p.m. ET
• Location: St. Louis, Missouri
• Stadium: Busch Stadium
• Favorite: Cardinals (-128)
• Underdog: Orioles (+113)
• Over/under: 8.5

How to Watch Cardinals vs. Orioles

• TV Channel: CARD and MASN
• Live Stream: Fubo (Watch for free)

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Cardinals vs. Orioles: Betting the Moneyline

• The Cardinals have put together a 23-18 record in games they were listed as the moneyline favorite (winning 56.1% of those games).
• Baltimore has come away with 31 wins in the 71 contests it has been listed as the underdogs in this season.
• St. Louis has a record of 8-6 in games when bookmakers favor them by at least -128 on the moneyline.
• The Orioles have a mark of 13-19 in contests where oddsmakers favor them by +113 or worse on the moneyline.
• The Cardinals have an implied moneyline win probability of 56.1% in this game.
• The moneyline set for this matchup implies the Orioles have a 46.9% chance of walking away with the win.

Cardinals vs. Orioles: Betting the Spread & Total

• The Cardinals have played in 132 games with set over/under, and have combined with opponents to go over the total 53 times (53-70-9).
• Baltimore and its opponents have hit the over in 66 of its 131 games with a total this season.
• The Cardinals have put together a 72-60-0 record ATS this season (covering 54.5% of the time).
• In 131 games with a line this season, the Orioles have a mark of 68-63-0 against the spread.