Mariners vs. Astros Dunkel MLB Picks, Predictions and Prop Bets - April 11

The Houston Astros hope to end their five-game losing run against the Seattle Mariners, at 9:40 p.m. ET on Saturday. Luis Castillo (0-0, 2.79 ERA) will start for the Mariners, who are 5-9 this season and fifth in the AL West. Lance McCullers (1-0, 3.27 ERA) is the expected starter for the Astros, who are 6-8 and fourth in the AL West.

The oddsmakers have spoken, making the Mariners (-151) a moderate moneyline favorite to beat the Astros (+127) at home. The game has an over/under set at 7.5 runs.

Mariners vs. Astros Odds, Game Time

• Game day: Saturday, April 11, 2026
• Game time: 9:40 p.m. ET
• Location: Seattle, Washington
• Stadium: T-Mobile Park
• Favorite: Mariners (-151)
• Underdog: Astros (+127)
• Over/under: 7.5

How to Watch Mariners vs. Astros

• TV Channel: SEAM and SCHN
• Live Stream: Fubo (Watch for free)

Bet now on FanDuel Sportsbook!

Mariners vs. Astros: Betting the Moneyline

• The Mariners have gone 4-7 in games they were listed as the moneyline favorite (winning 36.4% of those games).
• Houston has been pegged as an underdog in four games this year and has walked away with the win three times (75%) in those games.
• This season Seattle has won two of its six games when favored by at least -151 on the moneyline.
• This will be the worst odds to win that sportsbooks have given the Astros this season with a +127 moneyline set for this game.
• Based on this contest's moneyline, the Mariners' implied win probability is 60.2%.
• The Astros have an implied victory probability of 44.1% according to the moneyline set by sportsbooks for this matchup.

Mariners vs. Astros: Betting the Spread & Total

• The Mariners have had an over/under set by bookmakers 14 times, and have combined with opponents to go over the total in six of those games (6-8-0).
• Houston's games have gone over the total in 10 of its 14 chances.
• The Mariners have a 5-9-0 record ATS this season (covering only 35.7% of the time).
• The Astros are 6-8-0 against the spread in their 14 games with a line set by sportsbooks this season.