Mariners vs. White Sox Dunkel MLB Picks, Predictions and Prop Bets - May 20

The Seattle Mariners and Chicago White Sox play a rubber match on Wednesday at 4:10 p.m. ET, with the series deadlocked at 1-1. Emerson Hancock (3-2, 3.02 ERA) will start for the Mariners, who are 23-27 this season and third in the AL West. Sean Burke (2-3, 4.10 ERA) is expected to start for the White Sox, who are 25-23 and second in the AL Central.

The Mariners (-154) are moneyline favorites at home over the White Sox (+128). The over/under for this contest is 7.5.

Mariners vs. White Sox Odds, Game Time

• Game day: Wednesday, May 20, 2026
• Game time: 4:10 p.m. ET
• Location: Seattle, Washington
• Stadium: T-Mobile Park
• Favorite: Mariners (-154)
• Underdog: White Sox (+128)
• Over/under: 7.5

How to Watch Mariners vs. White Sox

• TV Channel: SEAM and CHSN
• Live Stream: Fubo (Watch for free)

Bet now on FanDuel Sportsbook!

Mariners vs. White Sox: Betting the Moneyline

• The Mariners have won 22 of the 46 games they were the moneyline favorite this season (47.8%).
• Chicago has been victorious in 23, or 53.5%, of the 43 contests it has been chosen as underdogs in this season.
• Seattle has entered 15 games this season favored by -154 or more and is 8-7 in those contests.
• This year, the White Sox have won eight of 17 games when listed as at least +128 or worse on the moneyline.
• The Mariners have a 60.6% chance to win this matchup based on the moneyline's implied probability.
• Sportsbooks have implied with the moneyline set for this matchup that the White Sox have a 43.9% chance of pulling out a win.

Mariners vs. White Sox: Betting the Spread & Total

• The Mariners have had an over/under set by oddsmakers 50 times, and have combined with opponents to go over the total in 22 of those games (22-26-2).
• Games involving Chicago have gone over the total set by bookmakers in 27 of 48 chances this season.
• The Mariners have put together an 18-32-0 record ATS this season (covering only 36% of the time).
• The White Sox are 28-20-0 against the spread in their 48 games with a line set by sportsbooks this season.