Giants vs. White Sox Dunkel MLB Picks, Predictions and Prop Bets - May 23

The San Francisco Giants hope to break their four-game losing run against the Chicago White Sox, on Saturday at 4:05 p.m. ET. Adrian Houser (2-4, 5.25 ERA) will start for the Giants, who are 20-31 this season and fourth in the NL West. Bryan Hudson (2-1, 1.57 ERA) is starting for the White Sox, who are 26-24 and second in the AL Central.

With the White Sox (+101) visiting, the Giants (-121) are a solid favorite on the moneyline. The game's over/under is set at 8.5.

Giants vs. White Sox Odds, Game Time

• Game day: Saturday, May 23, 2026
• Game time: 4:05 p.m. ET
• Location: San Francisco, California
• Stadium: Oracle Park
• Favorite: Giants (-121)
• Underdog: White Sox (+101)
• Over/under: 8.5

How to Watch Giants vs. White Sox

• TV Channel: NBCS-BA and CHSN
• Live Stream: Fubo (Watch for free)

Bet now on FanDuel Sportsbook!

Giants vs. White Sox: Betting the Moneyline

• The Giants have a 7-8 record in games they were favored on the moneyline (winning 46.7% of those games).
• Chicago has been pegged as an underdog in 44 games this year and has walked away with the win 23 times (52.3%) in those games.
• San Francisco has a record of 4-3 when favored by -121 or more by oddsmakers this season.
• The White Sox have a win-loss record of 19-19 when favored by +101 or worse by sportsbooks this year.
• The implied moneyline probablility in this matchup gives the Giants a 54.8% chance to win.
• The moneyline set for this matchup implies the White Sox have a 49.8% chance of coming away with a victory in the contest.

Giants vs. White Sox: Betting the Spread & Total

• The Giants have played in 51 games with a set over/under, and have combined with their opponents to go over the total 23 times (23-25-3).
• Games involving Chicago have gone over the total set by oddsmakers in 29 of 50 chances this season.
• The Giants have collected a 20-31-0 record against the spread this season (covering only 39.2% of the time).
• The White Sox are 30-20-0 against the spread in their 50 games with a line set by sportsbooks this season.