Padres vs. Pirates Dunkel MLB Picks, Predictions and Prop Bets - Aug. 26

The Pittsburgh Pirates have a 2-0 series lead and hope to sweep the San Diego Padres on Wednesday at Petco Park, at 4:10 p.m. ET. Randy Vasquez (9-6, 4.19 ERA) gets the start for the Padres, who are 71-62 this season and second in the NL West. Bubba Chandler (6-8, 4.38 ERA) is expected to start for the Pirates, who are 65-69 and fourth in the NL Central.

The Pirates (+117) are on the road versus the favored Padres (-132). The over/under for the Padres-Pirates game is 7.

Padres vs. Pirates Odds, Game Time

• Game day: Wednesday, August 26, 2026
• Game time: 4:10 p.m. ET
• Location: San Diego, California
• Stadium: Petco Park
• Favorite: Padres (-132)
• Underdog: Pirates (+117)
• Over/under: 7

How to Watch Padres vs. Pirates

• TV Channel: SDPA and SportsNet PT
• Live Stream: Fubo (Watch for free)

Bet now on FanDuel Sportsbook!

Padres vs. Pirates: Betting the Moneyline

• The Padres have been the moneyline favorite 60 total times this season. They've gone 34-26 in those games.
• Pittsburgh has been victorious in 26, or 40.6%, of the 64 contests it has been chosen as underdogs in this season.
• San Diego is 20-14 this season when entering a game favored by -132 or more on the moneyline.
• The Pirates have a mark of 12-14 in contests where oddsmakers favor them by +117 or worse on the moneyline.
• The Padres have a 56.9% chance to win this contest based on the moneyline's implied probability.
• The Pirates have an implied victory probability of 46.1% according to the moneyline set for this matchup.

Padres vs. Pirates: Betting the Spread & Total

• In the 133 games in which oddsmakers have set an over/under for the Padres, they have combined with opponents to go over the total 58 times (58-71-4).
• Pittsburgh and its opponents have hit the over in 72 of its 134 games with a total this season.
• The Padres have a 75-58-0 record against the spread this season (covering 56.4% of the time).
• The Pirates are 65-69-0 against the spread in their 134 games with a line set by sportsbooks this season.