Padres vs. Guardians Dunkel MLB Picks, Predictions and Prop Bets - Aug. 16

The San Diego Padres and Cleveland Guardians play a rubber match on Sunday at 1:40 p.m. ET, with the series deadlocked at 1-1. Casey Mize (4-7, 3.38 ERA) gets the start for the Padres, who are 66-58 this season and third in the NL West. Tanner Bibee (4-12, 3.99 ERA) is the expected starter for the Guardians, who are 60-64 and fourth in the AL Central.

The moneyline odds for the Padres (-112) versus the Guardians (-101) indicate a tight game. The game has an over/under set at 8.5 runs.

Padres vs. Guardians Odds, Game Time

• Game day: Sunday, August 16, 2026
• Game time: 1:40 p.m. ET
• Location: Cleveland, Ohio
• Stadium: Progressive Field
• Favorite: Padres (-112)
• Underdog: Guardians (-101)
• Over/under: 8.5

How to Watch Padres vs. Guardians

• TV Channel: CLEG and SDPA
• Live Stream: Fubo (Watch for free)

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Padres vs. Guardians: Betting the Moneyline

• The Padres have won 55.8% of the games this season when they were favored on the moneyline (29-23).
• Cleveland has been victorious in 26, or 51%, of the 51 contests it has been chosen as underdogs in this season.
• This season San Diego has won 28 of its 50 games, or 56%, when favored by at least -112 on the moneyline.
• This season, the Guardians have come away with a win 25 times in 46 chances when named as an underdog of at least -101 or worse on the moneyline.
• The implied moneyline probablility for this matchup gives the Padres a 52.8% chance to win.
• The Guardians have an implied victory probability of 50.2% according to the moneyline set for this matchup.

Padres vs. Guardians: Betting the Spread & Total

• The Padres have played in 124 games with an over/under set, and have combined with their opponents to go over the total 56 times (56-65-3).
• Cleveland's games have gone over the total in 60 of its 124 chances.
• The Padres are 68-56-0 ATS this season.
• The Guardians have an against the spread record of 60-64-0 in 124 games with a line this season.