Steelers vs. Colts Week 5 Dunkel NFL Picks, Predictions and Odds

The Pittsburgh Steelers (2-2) are considered favorites (-2.5) according to the point spread ahead of their game versus the Indianapolis Colts (2-2) on October 11, 2026, starting at 1 p.m. ET, airing on CBS. The matchup has an over/under of 44.5 points.

The Steelers are compiling 19.3 points per game on offense, which ranks them 23rd in the NFL. On the other side of the ball, they rank 14th, surrendering 21.8 points per contest. With 25.5 points per game on the offensive side of the ball, the Colts rank 13th in the NFL. On defense, they rank 22nd, giving up 26.0 points per contest.

Steelers vs. Colts Odds and Game Time

• Date: Sunday, October 11, 2026
• Time: 1 p.m. ET
• City: Pittsburgh, Pennsylvania
• Venue: Acrisure Stadium
• Total: 44.5 points
• Spread: Steelers -2.5
• Moneyline: Steelers (-142), Colts (+120)

How to watch Steelers vs. Colts

• TV Channel: CBS

Betting the Over/Under: Steelers vs. Colts

• The Steelers and their opponents have combined to score more than 44.5 points twice this season (in four games).
• Pittsburgh games have gone over the point total twice this season.
• The Colts and their opponents have scored more than 44.5 combined points twice this season.
• So far this season, two Indianapolis games have gone over the point total.
• These two teams score 44.8 points per game combined, 0.3 more than this game's point total.
• Combined, these teams surrender 47.8 points per game, 3.3 more points than this matchup's over/under.

Betting the Spread: Steelers vs. Colts

• Pittsburgh has a record of 2-2-0 against the spread this season.
• Pittsburgh has covered the spread once this season (1-1 ATS) when playing as at least 2.5-point favorites.
• The Colts are 3-1-0 ATS this year.
• Indianapolis has covered the spread once when an underdog by 2.5 points or more this season (in two opportunities).

Betting the Moneyline: Steelers vs. Colts

• Pittsburgh has been listed as the moneyline favorite only two other times so far this season, and they split the two games.
• The Colts have been underdogs in three games this season and won one (33.3%) of those contests.
• Pittsburgh has played as a moneyline favorite of -142 or shorter in only two games this season, and it split 1-1.
• This season, Indianapolis has been at least a +120 underdog on the moneyline two times, losing each of those contests.
• The Steelers have a 58.7% chance to win this game based on the moneyline's implied probability.

Dunkel Prediction for Steelers vs. Colts

For more expert NFL picks, visit our Dunkel Index NFL Picks and Predictions.