Pirates vs. Cardinals Dunkel MLB Picks, Predictions and Prop Bets - Sept. 24

The Pittsburgh Pirates and St. Louis Cardinals play a rubber match on Thursday at 12:35 p.m. ET, with the series deadlocked at 1-1. Paul Skenes (10-11, 3.91 ERA) will start for the Pirates, who are 80-78 this season and third in the NL Central. Kyle Leahy (10-5, 3.65 ERA) is expected to start for the Cardinals, who are 77-81 and fourth in the NL Central.

With the Cardinals (+135) visiting, the Pirates (-165) are a solid favorite on the moneyline. The game has an over/under of 6.5 runs.

Pirates vs. Cardinals Odds, Game Time

• Game day: Thursday, September 24, 2026
• Game time: 12:35 p.m. ET
• Location: Pittsburgh, Pennsylvania
• Stadium: PNC Park
• Favorite: Pirates (-165)
• Underdog: Cardinals (+135)
• Over/under: 6.5

How to Watch Pirates vs. Cardinals

• TV Channel: SportsNet PT and CARD
• Live Stream: Fubo (Watch for free)

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Pirates vs. Cardinals: Betting the Moneyline

• The Pirates are 48-34 in games they were listed as the moneyline favorite (winning 58.5% of those games).
• St. Louis has been victorious in 50, or 47.6%, of the 105 contests it has been chosen as underdogs in this season.
• Pittsburgh has a record of 11-7, a 61.1% win rate, when favored by -165 or more by bookmakers this season.
• The Cardinals have a mark of 14-15 in contests where sportsbooks favor them by +135 or worse on the moneyline.
• Based on this matchup's moneyline, the Pirates have an implied win probability of 62.3%.
• The Cardinals have an implied victory probability of 42.6% according to the moneyline set by oddsmakers for this matchup.

Pirates vs. Cardinals: Betting the Spread & Total

• The Pirates have had an over/under set by bookmakers 158 times, and have combined with opponents to go over the total in 80 of those games (80-71-7).
• St. Louis' games have gone over the total in 70 of its 158 chances.
• The Pirates have a 78-80-0 record against the spread this season (covering 49.4% of the time).
• The Cardinals have an against the spread mark of 86-72-0 in 158 games with a line this season.