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Phillies vs. Guardians Dunkel MLB Picks, Predictions and Prop Bets - May 23

23 May 2026 By Data Skrive

The Cleveland Guardians will look to keep a seven-game winning streak going when they visit the Philadelphia Phillies at 4:05 p.m. ET on Saturday. Zack Wheeler (3-0, 1.99 ERA) will start for the Phillies, who are 25-26 this season and second in the NL East. Slade Cecconi (3-4, 5.16 ERA) is starting for the Guardians, who are 31-22 and first in the AL Central.

With the Guardians (+157) visiting, the Phillies (-190) are a solid favorite on the moneyline. The total for this contest is set at 7.

Phillies vs. Guardians Odds, Game Time

  • Game day: Saturday, May 23, 2026
  • Game time: 4:05 p.m. ET
  • Location: Philadelphia, Pennsylvania
  • Stadium: Citizens Bank Park
  • Favorite: Phillies (-190)
  • Underdog: Guardians (+157)
  • Over/under: 7

How to Watch Phillies vs. Guardians

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Phillies vs. Guardians: Betting the Moneyline

  • The Phillies are 20-17 in games they were listed as the moneyline favorite (winning 54.1% of those games).
  • Cleveland has been underdogs in 24 games this season and has come away with the win 14 times (58.3%) in those contests.
  • Philadelphia has a record of 5-1 when favored by -190 or more by sportsbooks this season.
  • The Guardians have a mark of 2-2 in contests where oddsmakers favor them by +157 or worse on the moneyline.
  • Based on this game's moneyline, the Phillies' implied win probability is 65.5%.
  • Sportsbooks have implied with the moneyline set for this matchup that the Guardians have a 38.9% chance of pulling out a win.

Phillies vs. Guardians: Betting the Spread & Total

  • The Phillies have combined with opponents to hit the over on the total 24 times this season for a 24-25-2 record against the over/under.
  • Games involving Cleveland have gone over the total set by bookmakers in 26 of 53 chances this season.
  • The Phillies have put together a 16-35-0 record against the spread this season (covering just 31.4% of the time).
  • The Guardians are 30-23-0 against the spread in their 53 games that had a posted line this season.
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