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Twins vs. Astros Dunkel MLB Picks, Predictions and Prop Bets - May 19

19 May 2026 By Data Skrive

Josh Bell leads the Minnesota Twins into a contest against the Houston Astros a game after homering twice in a 6-3 victory over the Astros. It begins at 7:40 p.m. ET on Tuesday. Zebby Matthews (1-0, 0.00 ERA) will start for the Twins, who are 22-26 this season and third in the AL Central. Lance McCullers (2-3, 6.86 ERA) is expected to start for the Astros, who are 19-30 and fourth in the AL West.

The bookmakers have spoken, making the Twins (-136) a moderate moneyline favorite to defeat the Astros (+114) at home. The contest has an over/under set at 8.5.

Twins vs. Astros Odds, Game Time

  • Game day: Tuesday, May 19, 2026
  • Game time: 7:40 p.m. ET
  • Location: Minneapolis, Minnesota
  • Stadium: Target Field
  • Favorite: Twins (-136)
  • Underdog: Astros (+114)
  • Over/under: 8.5

How to Watch Twins vs. Astros

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Twins vs. Astros: Betting the Moneyline

  • The Twins have won six of the 14 games they were the moneyline favorite this season (42.9%).
  • Houston has come away with 14 wins in the 33 contests it has been listed as the underdogs in this season.
  • Minnesota has played as favorites of -136 or more once this season and lost that game.
  • The Astros have a mark of 8-13 in contests where bookmakers favor them by +114 or worse on the moneyline.
  • Based on this game's moneyline, the Twins have an implied win probability of 57.6%.
  • The moneyline set for this matchup implies the Astros have a 46.7% chance of walking away with the win.

Twins vs. Astros: Betting the Spread & Total

  • The Twins have combined with opponents to go over the total 27 times this season for a 27-18-3 record against the over/under.
  • Houston and its opponents have hit the over in 28 of its 49 games with a total this season.
  • The Twins have gone 25-23-0 ATS this season.
  • The Astros have posted a record of 19-30-0 against the spread this season.
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