Louisville vs. Virginia Tech Dunkel Predictions & Vegas Odds - Jan. 24

The No. 23 Louisville Cardinals (13-5, 3-3 ACC) host the Virginia Tech Hokies (15-5, 4-3 ACC) at KFC Yum! Center, tipping off at 2:15 p.m. ET on Saturday, January 24, 2026. The Cardinals are 11.5-point favorites in the game. The matchup's over/under is set at 159.5.

In its last outing on Saturday, Louisville earned a 100-59 victory over Pittsburgh. In Louisville's win, Ryan Conwell led the way with a team-high 24 points (adding six rebounds and six assists). In its last game on Wednesday, Virginia Tech earned a 76-74 win against Syracuse. Ben Hammond's team-leading 24 points paced Virginia Tech in the win.

Louisville vs. Virginia Tech Odds and Game Time

• When: Saturday, January 24, 2026 at 2:15 p.m. ET
• Where: KFC Yum! Center in Louisville, Kentucky
• Spread favorite: Louisville -11.5
• Moneyline favorite: Louisville -758
• Moneyline underdog: Virginia Tech +525
• Over/Under: 159.5 points

How to watch Louisville vs. Virginia Tech

• TV Channel: CW+ (WCBD - Charleston, SC)
• Live Stream: Fubo
• Check out the rest of our Dunkel Index NCAA Basketball Picks!

Betting the Over/Under: Louisville vs. Virginia Tech

• This season, Louisville and its opponents have combined to outscore Saturday's over/under of 159.5 points seven times.
• In Virginia Tech's 20 games this season, eight finished with more combined points than Saturday's total of 159.5.
• The point total for the game of 159.5 is 10.4 points fewer than the combined points per game averages for the Cardinals (87.9 points per game) and the Hokies (82.0 points per game).
• This matchup's total is 15.8 fewer points than the 143.7 these two teams combine to give up per game in 2024.
• On average, the over/under in Louisville's games is 2.0 fewer points than the over/under of 159.5 in this matchup.
• The over/under for this contest is 3.4 points higher than the average over/under in Virginia Tech's games this season of 156.1.

Betting the Spread: Louisville vs. Virginia Tech

• Louisville has played 18 games, with 10 wins against the spread.
• The Cardinals have an against the spread record of 5-3 in their eight games when favored by 11.5 points or more so far this season.
• Virginia Tech has played 20 games, with 12 wins against the spread.
• Louisville is 9-2 overall, and 6-5 against the spread, at home.
• At home, Louisville is 5-3 ATS as a 11.5-point favorite or greater.
• In away games, Virginia Tech is unbeaten against the spread and 2-2 overall.

Betting the Moneyline: Louisville vs. Virginia Tech

• This season, Louisville has won 12 out of the 15 games, or 80%, in which it has been the moneyline favorite.
• The Cardinals have entered seven games this season favored by -758 or more, and won each of those games.
• The sportsbooks' moneyline implies a 88.3% chance of a victory for Louisville.
• Virginia Tech has been a moneyline underdog in eight games this season and has come away with the win four times (50%) in those contests.
• The Hokies have yet to play a game this season with longer moneyline odds than +525.
• The moneyline set for this matchup implies Virginia Tech has a 16% chance of walking away with the win.